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Engineering large animal models of human diseaseRecent advances using zebrafish animal models for muscle disease drug discoveryGenetically modified pig models for neurodegenerative disorders.Functional analysis and transcriptional output of the Göttingen minipig genome.A porcine model of osteosarcoma.Pluripotent stem cells and livestock genetic engineering.Engineering Large Animal Species to Model Human DiseasesAdvances in genetic modification of farm animals using zinc-finger nucleases (ZFN).Molecular scissors and their application in genetically modified farm animals.Recent developments and clinical studies utilizing engineered zinc finger nuclease technology.Germline gene polymorphisms predisposing domestic mammals to carcinogenesis.Structural and molecular bases of rod photoreceptor morphogenesis and disease.Modification of the Genome of Domestic Animals.Establishment of a strain of haemophilia-A pigs by xenografting of foetal testicular tissue from neonatally moribund cloned pigs.Basics of genome editing technology and its application in livestock species.Use of ferrets for electrophysiologic monitoring of ion transport.Efficient generation of P53 biallelic knockout Diannan miniature pigs via TALENs and somatic cell nuclear transfer.Stem cells and genome editing: approaches to tissue regeneration and regenerative medicine.Generation of embryonic stem-like cells from in vivo-derived porcine blastocysts at a low concentration of basic fibroblast growth factor.Expression of the Alzheimer's Disease Mutations AβPP695sw and PSEN1M146I in Double-Transgenic Göttingen Minipigs.Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells.Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Genetically modified pigs to model human diseases.
@en
type
label
Genetically modified pigs to model human diseases.
@en
prefLabel
Genetically modified pigs to model human diseases.
@en
P2860
P1476
Genetically modified pigs to model human diseases.
@en
P2093
Alexander Kind
Tatiana Flisikowska
P2860
P2888
P356
10.1007/S13353-013-0182-9
P577
2014-02-01T00:00:00Z