The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc.
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Proteoglycan form and function: A comprehensive nomenclature of proteoglycansHijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic PhenotypesHyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell ExteriorRoles of Proteoglycans and Glycosaminoglycans in Wound Healing and FibrosisRegulation of hyaluronan synthesis in vascular diseases and diabetesA current view of perlecan in physiology and pathology: A mosaic of functions.CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention.O-GlcNAc and the epigenetic regulation of gene expression.Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking.Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid Synthesis4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.Periostin induces intracellular cross-talk between kinases and hyaluronan in atrioventricular valvulogenesis.Epigenetics in extracellular matrix remodeling and hyaluronan metabolism.Biology and biotechnology of hyaluronan.MDA-MB-231 breast cancer cell viability, motility and matrix adhesion are regulated by a complex interplay of heparan sulfate, chondroitin-/dermatan sulfate and hyaluronan biosynthesis.4-methylumbelliferone and imatinib combination enhances senescence induction in chronic myeloid leukemia cell lines.UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression.Drug-Mediated Regulation of Glycosaminoglycan Biosynthesis.Hyaluronan 35kDa treatment protects mice from Citrobacter rodentium infection and induces epithelial tight junction protein ZO-1 in vivo.Endorepellin-evoked Autophagy Contributes to Angiostasis.Hyperglycemia diverts dividing stem cells to pathological adipogenesis.N-acetylglucosamine: more than a silent partner in insulin resistance.Hyaluronan synthase assembles hyaluronan on a [GlcNAc(β1,4)]n-GlcNAc(α1→)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end.Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif.Layilin is critical for mediating hyaluronan 35kDa-induced intestinal epithelial tight junction protein ZO-1 in vitro and in vivo.Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan.The pericellular hyaluronan of articular chondrocytes.Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth.
P2860
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P2860
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc.
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type
label
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc.
@en
prefLabel
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc.
@en
P2093
P2860
P1433
P1476
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc
@en
P2093
Aimin Wang
Gerald W Hart
Markku Tammi
Raija Tammi
Richard W Hanson
Sanna Oikari
Vincent C Hascall
P2860
P356
10.1016/J.MATBIO.2014.01.014
P577
2014-01-30T00:00:00Z