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Effect of silencing HOXA5 gene expression using RNA interference on cell cycle and apoptosis in Jurkat cells.Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature.Higher expression levels of the HOXA9 gene, closely associated with MLL-PTD and EZH2 mutations, predict inferior outcome in acute myeloid leukemia.Microarray-based analysis and clinical validation identify ubiquitin-conjugating enzyme E2E1 (UBE2E1) as a prognostic factor in acute myeloid leukemia.RARA fusion genes in acute promyelocytic leukemia: a review.Deregulation of the HOXA9/MEIS1 axis in acute leukemia.Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion.HOXA9 is critical in the proliferation, differentiation, and malignancy of leukaemia cells both in vitro and in vivo.A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways
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description
article científic
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article scientifique
@fr
articol științific
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articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Hox gene dysregulation in acute myeloid leukemia.
@en
type
label
Hox gene dysregulation in acute myeloid leukemia.
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prefLabel
Hox gene dysregulation in acute myeloid leukemia.
@en
P2093
P2860
P356
P1433
P1476
Hox gene dysregulation in acute myeloid leukemia.
@en
P2093
Audrey Basinko
Etienne De Braekeleer
Frédéric Morel
Marc De Braekeleer
Marie-Josée Le Bris
Nathalie Douet-Guilbert
P2860
P304
P356
10.2217/FON.13.195
P407
P577
2014-02-01T00:00:00Z