Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases. - Wikidata - wikimedia - TriplyDB

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

http://www.wikidata.org/entity/Q38191981

about

Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01 Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.NAD+ augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling.Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions.Effect of adriamycin on BRCA1 and PARP-1 expression in MCF-7 breast cancer cells.DNA damage response markers are differentially expressed in BRCA-mutated breast cancers Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients.PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway Novel PARP-1 Inhibitor Scaffolds Disclosed by a Dynamic Structure-Based Pharmacophore Approach.Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans.Reverse the Resistance to PARP Inhibitors.HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity Studies A Study on the Anticarcinogenic Effects of Calcium Fructoborate.Insight into the machinery that oils chromatin dynamics.The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.Kynurenine pathway metabolism and neuroinflammatory disease.Benzimidazole Scaffold as Anticancer Agent: Synthetic Approaches and Structure-Activity Relationship.Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b.Inhibitory effect of black tea pigments, theaflavin‑3/3'-gallate against cisplatin-resistant ovarian cancer cells by inducing apoptosis and G1 cell cycle arrest.Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line.Anti-apoptotic effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, against multiple organ damage induced by gamma irradiation in rats.Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.Cancer: Towards a general theory of the target: All successful cancer therapies, actual or potential, are reducible to either (or both) of two fundamental strategies.Automodification of PARP and fatty acid-based membrane lipidome as a promising integrated biomarker panel in molecular medicine.NAD + biosynthesis, aging, and disease.Role of IGF-1R in ameliorating apoptosis of GNE deficient cells.Aberrations of DNA Repair Pathways in Prostate Cancer: Future Implications for Clinical Practice?Response to olaparib in metastatic castration-resistant prostate cancer with germline BRCA2 mutation: a case report Poly(ADP-ribose) polymerase 1 searches DNA via a 'monkey bar' mechanism

P2860

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P2860

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

http://www.wikidata.org/entity/Q38191981

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Review of poly (ADP-ribose) po ...... in cancer and other diseases.

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CRITREVEUKARYOTGENEEXPR.2013006875

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Critical Reviews in Eukaryotic Gene Expression

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Review of poly (ADP-ribose) po ...... g in cancer and other diseases

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David A Boothman

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Erik A Bey

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Farjana J Fattah

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Jinming Gao

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Longshan Li

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Malina Patel

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Ying Dong

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P2860

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

Advances in using PARP inhibitors to treat cancer

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

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15-28

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10.1615/CRITREVEUKARYOTGENEEXPR.2013006875

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1

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24

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Julio C Morales

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2014-01-01T00:00:00Z

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24579667

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4806654

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