about
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP153BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.XRN2 Links Transcription Termination to DNA Damage and Replication Stress.The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repairDNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.53BP1 oligomerization is independent of its methylation by PRMT1.H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability
P50
Q28215916-F04DF31D-91AF-441C-BA41-045B36D6685BQ29465548-AFD5AB49-8B71-4655-A9DA-065AD67B7788Q30947641-0D86E950-1A24-4347-8447-22E940CA59B0Q33767952-85450399-1734-4337-A608-28E3BBFF3F0BQ34480292-A03C952B-6D4B-457F-B623-AC9F2779F605Q36082634-CFA78B1D-26C5-4869-A880-A7BB43E0DBBCQ36627936-AE45D77C-619E-4D22-87FE-3DE0A974830FQ37602208-EB591448-3BDC-4F48-83A8-48C0C9C212FAQ37734389-FDF7D3D2-0BAD-436B-AAF6-A8E985ECDEE0Q38191981-26596B21-0534-4495-AFFC-466B4ED6227AQ39982450-AD1A451E-4237-4FB4-B4BD-6BEA496A9556Q41175947-75499A13-5D2C-440A-B675-7A47E6BB955AQ46809487-52E22334-40F9-4A38-9336-F0D65095C673Q46904251-CB373607-BD3A-446B-B52A-7D62962D4A12Q78960906-9ADFBBA2-374E-4CB5-80C6-89B0F87C875F
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Julio C Morales
@ast
Julio C Morales
@en
Julio C Morales
@es
Julio C Morales
@nl
type
label
Julio C Morales
@ast
Julio C Morales
@en
Julio C Morales
@es
Julio C Morales
@nl
prefLabel
Julio C Morales
@ast
Julio C Morales
@en
Julio C Morales
@es
Julio C Morales
@nl
P108
P106
P1153
35339651200
P21
P31
P496
0000-0002-0854-7866