Connexins: sensors of epidermal integrity that are therapeutic targets.
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Recent advances in understanding ichthyosis pathogenesisThe p.Cys169Tyr variant of connexin 26 is not a polymorphismDominant De Novo Mutations in GJA1 Cause Erythrokeratodermia Variabilis et Progressiva, without Features of Oculodentodigital Dysplasia.Connexin 43 deficiency accelerates skin wound healing and extracellular matrix remodeling in mice.Dominant de novo DSP mutations cause erythrokeratodermia-cardiomyopathy syndrome.Defective channels lead to an impaired skin barrier.Mechanisms linking connexin mutations to human diseases.Connexins: junctional and non-junctional modulators of proliferation.Connexins and skin disease: insights into the role of beta connexins in skin homeostasis.An updated review of mechanotransduction in skin disorders: transcriptional regulators, ion channels, and microRNAs.Connexin43 plays diverse roles in co-ordinating cell migration and wound closure events.Connexins and pannexins in the integumentary system: the skin and appendages.Connexin channels in congenital skin disorders.Connexins and their channels in inflammation.Connexin 43: Key roles in the skinInhibitors of connexin and pannexin channels as potential therapeutics.Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in miceConnexin hemichannels influence genetically determined inflammatory and hyperproliferative skin diseases.Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations.Connexin 43 Hemichannels Regulate the Expression of Wound Healing-Associated Genes in Human Gingival Fibroblasts.Induction of cell death and gain-of-function properties of connexin26 mutants predict severity of skin disorders and hearing loss.Connexin Communication Compartments and Wound Repair in Epithelial Tissue.
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Connexins: sensors of epidermal integrity that are therapeutic targets.
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article científic
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article scientifique
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articol științific
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Connexins: sensors of epidermal integrity that are therapeutic targets.
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Connexins: sensors of epidermal integrity that are therapeutic targets.
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Connexins: sensors of epidermal integrity that are therapeutic targets.
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Connexins: sensors of epidermal integrity that are therapeutic targets.
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Catherine S Wright
Jennifer A Easton
Malcolm B Hodgins
Patricia E Martin
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P304
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10.1016/J.FEBSLET.2014.02.048
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P577
2014-03-04T00:00:00Z