Protein ADP-ribosylation and the cellular response to DNA strand breaks.
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Connecting the Dots: From DNA Damage and Repair to AgingThe structural basis of XRCC1-mediated DNA repairSerine ADP-Ribosylation Depends on HPF1DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repairThe XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function.Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.Coordinated Regulation of TIP60 and Poly(ADP-Ribose) Polymerase 1 in Damaged-Chromatin Dynamics.Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.The rise and fall of poly(ADP-ribose): An enzymatic perspective.Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials.A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1.ATM induces MacroD2 nuclear export upon DNA damageOverlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.A randomized Phase II study of veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in BRCA1/2 metastatic breast cancer: design and rationale.Structure of transcribed chromatin is a sensor of DNA damage.PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2)Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase.PARP inhibition causes premature loss of cohesion in cancer cells.Specificity of reversible ADP-ribosylation and regulation of cellular processes.Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.Studies on DNA Damage Repair and Precision Radiotherapy for Breast Cancer.Dna is a New Target of Parp3.Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in BRCA-Mutant Ovarian Cancer Models.ADPRtool: A novel predicting model for identification of ASP-ADP-Ribosylation sites of human proteins.Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis
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P2860
Protein ADP-ribosylation and the cellular response to DNA strand breaks.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Protein ADP-ribosylation and the cellular response to DNA strand breaks.
@en
type
label
Protein ADP-ribosylation and the cellular response to DNA strand breaks.
@en
prefLabel
Protein ADP-ribosylation and the cellular response to DNA strand breaks.
@en
P1433
P1476
Protein ADP-ribosylation and the cellular response to DNA strand breaks.
@en
P2093
K W Caldecott
P304
P356
10.1016/J.DNAREP.2014.03.021
P577
2014-04-20T00:00:00Z