about
Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple MyelomaWIP1 phosphatase as pharmacological target in cancer therapy.Identification of inhibitors of biological interactions involving intrinsically disordered proteins.Targeting Transcription Factors in CancerIs MDM2 SNP309 Variation a Risk Factor for Head and Neck Carcinoma?: An Updated Meta-Analysis Based on 11,552 Individuals.Influence of MDM2 polymorphisms on squamous cell carcinoma susceptibility: a meta-analysis.Essential Roles of E3 Ubiquitin Ligases in p53 Regulation.Battle against cancer: an everlasting saga of p53.Targeting tumor suppressor genes for cancer therapy.Dysfunction of the MDM2/p53 axis is linked to premature aging.5-aza-2',2'-Difluroro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of CancerA stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.Imidazoline scaffold in medicinal chemistry: a patent review (2012-2015).Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.Negative auto-regulators trap p53 in their web.p53 and RAD9, the DNA Damage Response, and Regulation of Transcription Networks.A phase I trial of the human double minute 2 inhibitor (MK-8242) in patients with refractory/recurrent acute myelogenous leukemia (AML).In silico structure-based approaches to discover protein-protein interaction-targeting drugs.p53 Gene (NY-CO-13) Levels in Patients with Chronic Myeloid Leukemia: The Role of Imatinib and Nilotinib.Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects.Butein activates p53 in hepatocellular carcinoma cells via blocking MDM2-mediated ubiquitination.MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells.The Roles of MDM2 and MDMX in Cancer.NUC041, a Prodrug of the DNA Methytransferase Inhibitor 5-aza-2',2'-Difluorodeoxycytidine (NUC013), Leads to Tumor Regression in a Model of Non-Small Cell Lung Cancer.Potential use of compounds from sea cucumbers as MDM2 and CXCR4 inhibitors to control cancer cell growth
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Targeting p53-MDM2-MDMX loop for cancer therapy.
@en
type
label
Targeting p53-MDM2-MDMX loop for cancer therapy.
@en
prefLabel
Targeting p53-MDM2-MDMX loop for cancer therapy.
@en
P2093
P2860
P1476
Targeting p53-MDM2-MDMX loop for cancer therapy.
@en
P2093
P2860
P304
P356
10.1007/978-94-017-9211-0_16
P577
2014-01-01T00:00:00Z