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Human inositol 1,4,5-trisphosphate type-1 receptor, InsP3R1: structure, function, regulation of expression and chromosomal localizationFunctional relationship between cyclic AMP-dependent protein phosphorylation and platelet inhibitionThrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human plateletsThrombin activation of human platelets dissociates a complex containing gelsolin and actin from phosphatidylinositide-specific phospholipase Cgamma1The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contactsLoss of ATP diphosphohydrolase activity with endothelial cell activationSignal-dependent translation of a regulatory protein, Bcl-3, in activated human plateletsHyperkalemic cardioplegia for adult and pediatric surgery: end of an era?Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylationExpression and mutagenesis of the catalytic domain of cGMP-inhibited phosphodiesterase (PDE3) cloned from human plateletsPrimary and secondary agonists can use P2X(1) receptors as a major pathway to increase intracellular Ca(2+) in the human plateletArachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombinActivation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse plateletsSynergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human plateletsCalcium-activated potassium channels in human plateletsA molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation.Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque.Multiscale simulation of thrombus growth and vessel occlusion triggered by collagen/tissue factor using a data-driven model of combinatorial platelet signalling.A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene.Mlck1a is expressed in zebrafish thrombocytes and is an essential component of thrombus formation.Systems modeling of Ca(2+) homeostasis and mobilization in platelets mediated by IP3 and store-operated Ca(2+) entryDifferential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets.Platelet secretion from dense and alpha-granules in vitro in migraine with or without aura.Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesionsSelective and rapid monitoring of dual platelet inhibition by aspirin and P2Y12 antagonists by using multiple electrode aggregometry.The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function.Piperine inhibits the activities of platelet cytosolic phospholipase A2 and thromboxane A2 synthase without affecting cyclooxygenase-1 activity: different mechanisms of action are involved in the inhibition of platelet aggregation and macrophage infThe effects of varying doses of aspirin on human platelet activation induced by PAF, collagen and arachidonic acid.Platelets: still a therapeutical target for haemostatic disorders.Deletion of the serotonin transporter in rats disturbs serotonin homeostasis without impairing liver regeneration.Effects of dextroamphetamine, lithium chloride, sodium valproate and carbamazepine on intraplatelet Ca2+ levels.Cyclic nucleotides attenuate thrombin-evoked alterations in parameters of platelet Na/H antiport. The role of cytosolic Ca.Platelet concentrate in bovine reproduction: effects on in vitro embryo production and after intrauterine administration in repeat breeder cowsRegulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.P1,P4-dithio-P2,P3-monochloromethylene diadenosine 5',5'''-P1,P4-tetraphosphate: a novel antiplatelet agent.Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.Oncocalyxone A inhibits human platelet aggregation by increasing cGMP and by binding to GP Ibalpha glycoproteinRole of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.Antiplatelet drugs in cardiological practice: established strategies and new developmentsOxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways
P2860
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P2860
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Molecular mechanisms of platelet activation.
@en
type
label
Molecular mechanisms of platelet activation.
@en
prefLabel
Molecular mechanisms of platelet activation.
@en
P1476
Molecular mechanisms of platelet activation.
@en
P2093
P304
P356
10.1152/PHYSREV.1989.69.1.58
P577
1989-01-01T00:00:00Z