Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.
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The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contactsThe proline-rich focal adhesion and microfilament protein VASP is a ligand for profilinsRoles for both cyclic GMP and cyclic AMP in the inhibition of collagen-induced platelet aggregation by nitroprussideMaturation depresses cGMP-mediated decreases in [Ca2+]i and Ca2+ sensitivity in ovine cranial arteries.Inhibitors of platelet signal transduction as anti-aggregatory drugs.Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate.The specific role of cGMP in hippocampal LTP.Complex inhibitory effects of nitric oxide on autophagyAtriopeptin, sodium azide and cyclic GMP reduce secretion of aqueous humour and inhibit intracellular calcium release in bovine cultured ciliary epithelium.Emerging roles for P2X1 receptors in platelet activation.Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase.Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate productionNitric oxide/cGMP pathway stimulates phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, in the substantia nigraEnhanced nitric oxide and cyclic GMP formation plays a role in the anti-platelet activity of simvastatinNatriuretic peptides and cardiovascular damage in the metabolic syndrome: molecular mechanisms and clinical implications.The P2X1 receptor and platelet function.Nitric oxide inhibits capacitative Ca2+ entry and enhances endoplasmic reticulum Ca2+ uptake in bovine vascular endothelial cells.A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin-based cytoskeleton of mammalian cells.An unsuspected property of natriuretic peptides: promotion of calcium-dependent catecholamine release via protein kinase G-mediated phosphodiesterase type 3 inhibition.Proabsorptive and prosecretory roles for nitric oxide in cholera toxin induced secretion.Reversal of radiation-induced cisplatin resistance in murine fibrosarcoma cells by selective modulation of the cyclic GMP-dependent transduction pathway.Photoaffinity labelling of cyclic GMP-binding proteins in human platelets.Platelet Ca(2+) responses coupled to glycoprotein VI and Toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca(2+) storesDefective smooth muscle regulation in cGMP kinase I-deficient mice.Nitric oxide controls src kinase activity through a sulfhydryl group modification-mediated Tyr-527-independent and Tyr-416-linked mechanism.Role of cyclic nucleotides in store-mediated external Ca2+ entry in human platelets.Nitric oxide stimulates tyrosine phosphorylation in murine fibroblasts in the absence and presence of epidermal growth factor.Nitric oxide action on growth factor-elicited signals. Phosphoinositide hydrolysis and [Ca2+]i responses are negatively modulated via a cGMP-dependent protein kinase I pathway.Ca2+ influx in platelets: activation by thrombin and by the depletion of the stores. Effect of cyclic nucleotides.Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I.Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets.Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants.Exogenous NO triggers preconditioning via a cGMP- and mitoKATP-dependent mechanism.Biochemical properties and cellular localization of the Drosophila DG1 cGMP-dependent protein kinase.Effects of cyclic nucleotides and protein kinases on platelet calcium homeostasis and mobilization.Calcium signalling in platelets and other cells.Expression of cGMP-dependent protein kinase I and its substrate VASP in neointimal cells of the injured rat carotid artery.Lysophosphatidylcholine causes cGMP-dependent verapamil-sensitive Ca2+ influx in vascular smooth muscle cells.cGMP inhibits IP3-induced Ca2+ release in intact rat megakaryocytes via cGMP- and cAMP-dependent protein kinases.
P2860
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P2860
Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@ast
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@en
type
label
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@ast
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@en
prefLabel
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@ast
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@en
P2093
P2860
P356
P1476
Role of cGMP and cGMP-dependen ...... elevation in human platelets.
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.3.1031
P407
P577
1992-02-01T00:00:00Z