Structural mechanisms of human RecQ helicases WRN and BLM.
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The short-lived African turquoise killifish: an emerging experimental model for ageingMechanisms of Origin, Phenotypic Effects and Diagnostic Implications of Complex Chromosome RearrangementsA helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells.WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational ProspectsThe Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation.Bloom's Syndrome: Clinical Spectrum, Molecular Pathogenesis, and Cancer Predisposition.Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.Different non-synonymous polymorphisms modulate the interaction of the WRN protein to its protein partners and its enzymatic activities.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.The Human RecQ4 Helicase Contains a Functional RecQ C-terminal Region (RQC) That Is Essential for Activity.RecQ helicase BLM regulates prostate cancer cell proliferation and apoptosis.Site-directed mutants of human RECQ1 reveal functional importance of the zinc binding domainHelicases and human diseases.The Expression of Checkpoint and DNA Repair Genes in Head and Neck Cancer as Possible Predictive Factors.
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P2860
Structural mechanisms of human RecQ helicases WRN and BLM.
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2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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name
Structural mechanisms of human RecQ helicases WRN and BLM.
@en
type
label
Structural mechanisms of human RecQ helicases WRN and BLM.
@en
prefLabel
Structural mechanisms of human RecQ helicases WRN and BLM.
@en
P2860
P356
P1476
Structural mechanisms of human RecQ helicases WRN and BLM.
@en
P2093
Ken Kitano
P2860
P356
10.3389/FGENE.2014.00366
P577
2014-10-29T00:00:00Z