Mannose 6-phosphate receptors and lysosomal enzyme targeting.
about
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.Correction of mucopolysaccharidosis type IIIb fibroblasts by lentiviral vector-mediated gene transferCation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domainIntracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surfaceComplex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamineSorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transportDecreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cellsDown-regulation of the M6P/IGF-II receptor increases cell proliferation and reduces apoptosis in neonatal rat cardiac myocytesThe Potential Role of the Proteases Cathepsin D and Cathepsin L in the Progression and Metastasis of Epithelial Ovarian CancerNeutrophils in innate host defense against Staphylococcus aureus infectionsImpact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transductionCompartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutantThe role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sortingOverexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturationReceptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry diseaseMannose 6-phosphate receptor and sortilin mediated endocytosis of α-galactosidase A in kidney endothelial cellsEnzyme replacement in a human model of mucopolysaccharidosis IVA in vitro and its biodistribution in the cartilage of wild type miceThe secretory pathway of protists: spatial and functional organization and evolutionMutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatusLong-term amelioration of feline Mucopolysaccharidosis VI after AAV-mediated liver gene transferA role for clathrin in the sorting of vacuolar proteins in the Golgi complex of yeastMolecular basis of variant pseudo-hurler polydystrophy (mucolipidosis IIIC)Introduction of Stuart KornfeldCholesterol dependence of varicella-zoster virion entry into target cellsO-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.A kinase associated with chromatin that can be activated by ligand-p185c-Neu or epidermal growth factor-receptor interactions.Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type IAdeno-associated viral vector-mediated gene transfer results in long-term enzymatic and functional correction in multiple organs of Fabry mice.Successful induction of immune tolerance to enzyme replacement therapy in canine mucopolysaccharidosis ITargeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy.Intrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis IEndocytosed cation-independent mannose 6-phosphate receptor traffics via the endocytic recycling compartment en route to the trans-Golgi network and a subpopulation of late endosomes.Role of mannose-6-phosphate receptors in herpes simplex virus entry into cells and cell-to-cell transmission.Enzyme replacement in a canine model of Hurler syndrome.Recovery of function in Chinese hamster ovary cell mutants with temperature-sensitive defects in vacuolar acidification.Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathwaysThe plant vacuolar sorting receptor AtELP is involved in transport of NH(2)-terminal propeptide-containing vacuolar proteins in Arabidopsis thaliana.Clathrin heavy chain functions in sorting and secretion of lysosomal enzymes in Dictyostelium discoideum.The 17-residue transmembrane domain of beta-galactoside alpha 2,6-sialyltransferase is sufficient for Golgi retention.
P2860
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P2860
Mannose 6-phosphate receptors and lysosomal enzyme targeting.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Mannose 6-phosphate receptors and lysosomal enzyme targeting.
@en
type
label
Mannose 6-phosphate receptors and lysosomal enzyme targeting.
@en
prefLabel
Mannose 6-phosphate receptors and lysosomal enzyme targeting.
@en
P2093
P1476
Mannose 6-phosphate receptors and lysosomal enzyme targeting.
@en
P2093
P304
12115-12118
P407
P577
1989-07-01T00:00:00Z