Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene.
about
Next-Generation Sequencing in the Mycology LabEmergence of azole-resistant aspergillus fumigatus strains due to agricultural azole use creates an increasing threat to human healthSterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding ComplexAzole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatusDiscovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossingIn vivo efficacy of a synthetic coumarin derivative in a murine model of aspergillosisAntifungal Therapy: New Advances in the Understanding and Treatment of MycosisFungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.In vitro antifungal susceptibilities of isolates of Candida spp. and Aspergillus spp. from China to nine systemically active antifungal agents: data from the SENTRY antifungal surveillance program, 2010 through 2012.A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence.First detection of TR46/Y121F/T289A and TR34/L98H alterations in Aspergillus fumigatus isolates from azole-naive patients in Denmark despite negative findings in the environment.Passive surveillance for azole-resistant Aspergillus fumigatus, United States, 2011-2013Resistance to antifungals that target CYP51.Clonal expansion and emergence of environmental multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR₃₄/L98H mutations in the cyp51A gene in India.Composite survival index to compare virulence changes in azole-resistant Aspergillus fumigatus clinical isolates.The strength of synergistic interaction between posaconazole and caspofungin depends on the underlying azole resistance mechanism of Aspergillus fumigatus.Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013Prevalence and mechanism of triazole resistance in Aspergillus fumigatus in a referral chest hospital in Delhi, India and an update of the situation in AsiaAntifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, JapanEvidence for genetic differentiation and variable recombination rates among Dutch populations of the opportunistic human pathogen Aspergillus fumigatus.Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome SequencingMultiple cyp51A-based mechanisms identified in azole-resistant isolates of Aspergillus fumigatus from China.Molecular epidemiology of Aspergillus fumigatus isolates harboring the TR34/L98H azole resistance mechanism.Azole preexposure affects the Aspergillus fumigatus population in patients.In Vitro Activity of ASP2397 against Aspergillus Isolates with or without Acquired Azole Resistance Mechanisms.Pharmacodynamics of anidulafungin against clinical Aspergillus fumigatus isolates in a nonneutropenic murine model of disseminated aspergillosis.In vitro interaction of voriconazole and anidulafungin against triazole-resistant Aspergillus fumigatus.Pharmacodynamics and dose-response relationships of liposomal amphotericin B against different azole-resistant Aspergillus fumigatus isolates in a murine model of disseminated aspergillosisIs azole resistance in Aspergillus fumigatus a problem in Spain?cyp51A-Based mechanisms of Aspergillus fumigatus azole drug resistance present in clinical samples from Germany.Direct Molecular Diagnosis of Aspergillosis and CYP51A Profiling from Respiratory Samples of French PatientsEpidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus Isolates from China.Incidence density of invasive fungal infections during primary antifungal prophylaxis in newly diagnosed acute myeloid leukemia patients in a tertiary cancer center, 2009 to 2011Global Population Genetic Analysis of Aspergillus fumigatus.Triazole Resistance in Aspergillus fumigatus Clinical Isolates Obtained in Nanjing, China.Efficacy and safety of current drug therapies for invasive aspergillosis.Invasive aspergillosis: resistance to antifungal drugs.Polymerase chain reaction-based assays for the diagnosis of invasive fungal infections.Azole resistance in Aspergillus: global status in Europe and Asia.
P2860
Q26746024-B51335D8-6095-48EF-B856-DBBF2707EB5DQ26999421-53377F99-FF09-4783-B1F0-F70111340DC4Q27312432-3CCA551D-FBB4-4E2E-92B9-956409701BF8Q28082352-B8CB2A8B-3590-47CC-98D4-B96C83A7581DQ28481341-66F4E9F4-E0A5-40D5-B032-EF54DFB36622Q28485433-8127ECFA-15C9-4BED-8835-FD062E030AF4Q28542402-747DE958-A1A4-46F7-922A-5CFCFD8A5180Q28818603-9E78E36B-5022-485E-BE0D-1B5D9469AF3FQ30318077-E7259366-E6FD-4F8D-BFBC-2CC8FEDD10FBQ30902025-C448DAE5-0CAF-4B6A-9F48-06DBAE12D00AQ33843857-2195326B-0121-4CFE-9D1B-3B14DEED1B0CQ34057414-BCBC45A5-79A2-4A83-B4E7-9B59E911D3BEQ34259732-2DFED5D8-90AF-4485-8C8A-F68F77287998Q34276700-25DDAAA5-83E0-4932-86D3-A0B18FA5335FQ34534761-2B6B6D13-F251-41FC-9E0A-ABAE189F8039Q34977071-3999B17E-B13C-4C0B-80E1-4C1C1F32204BQ35076940-1711C9DE-2DBF-4F41-90DA-C4847713C792Q35215022-B3D4C6A3-F377-496D-9B52-33B5D084DB48Q35585364-A0A80413-DE7B-4339-A914-8388C6777B91Q35666518-3F3166C8-DF5F-4F51-9C39-8CF7D7A84304Q35673582-490B6A46-7D61-47A4-9F7C-01D06B6CAC81Q35676292-780D083E-AABC-41BC-AEEB-C996B70458EDQ35746043-8D07F28A-5FFC-4F70-8082-AD84C7B607DBQ36171422-8A459CB4-4921-4F2C-B90D-AB8466CB3F9CQ36172445-DFCB52F8-423D-48D6-AABA-BBCB554D5794Q36439109-6A056B61-0419-446C-8413-4429CCCF5B11Q36505281-1DC7E463-3F45-4BC4-A47F-29EC872707F4Q36558484-A99C7467-83E9-4C8C-8C4E-69C588B50842Q36757621-A495C0DF-F044-4087-860C-E324537AF191Q37026702-445C593F-39F9-43B8-9535-F2571143D7C1Q37036556-E1EA34A8-4ED1-4DC9-A465-32A48436E75EQ37136645-FE73AB43-6CE0-4F8A-9E52-0C3E2C555968Q37287782-57704B39-BE19-4FB1-8D92-5CD6EE6BACD4Q37544662-1916ABA8-0AF3-4CCD-B29F-A4ACBAB61E37Q37620315-F1925058-6AEB-488C-89A4-28F8BCB725A2Q37711652-AAF880BA-774D-4535-872A-86CA509E8863Q37944001-763547EB-2EA0-4E24-8820-A3CB2A8C5FA1Q37983464-F886A515-B81B-4A39-B6B8-61486A8D30B1Q37987893-6B66B387-CEF9-408D-8913-0FF48BDA9717Q38066613-071F8439-B488-4245-A5DE-460B054B5CB5
P2860
Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Azole resistance in Aspergillu ...... H mutation in the cyp51A gene.
@en
type
label
Azole resistance in Aspergillu ...... H mutation in the cyp51A gene.
@en
prefLabel
Azole resistance in Aspergillu ...... H mutation in the cyp51A gene.
@en
P2093
P2860
P50
P356
P1476
Azole resistance in Aspergillu ...... H mutation in the cyp51A gene.
@en
P2093
João P Frade
Kizee A Etienne
S Arunmozhi Balajee
P2860
P304
P356
10.1128/AAC.00185-11
P407
P577
2011-06-20T00:00:00Z