SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation.
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The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break responseRNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sitesHistone demethylases in chromatin biology and beyondGogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.The nuclear import of ribosomal proteins is regulated by mTORA comprehensive method for detecting ubiquitinated substrates using TR-TUBE.Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.It is not all about BRCA: Cullin-Ring ubiquitin Ligases in ovarian cancer.Proteomics and transcriptomics analyses of Arabidopsis floral buds uncover important functions of ARABIDOPSIS SKP1-LIKE1.Adipocyte nuclei captured from VAT and SATF-box protein FBXO22 mediates polyubiquitination and degradation of KLF4 to promote hepatocellular carcinoma progression.Understanding cullin-RING E3 biology through proteomics-based substrate identificationSCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation.Regulation of Transient Site-specific Copy Gain by MicroRNA.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsSubsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine.Dissociation of the H3K36 demethylase Rph1 from chromatin mediates derepression of environmental stress-response genes under genotoxic stress in Saccharomyces cerevisiae.The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20F-Box Protein FBXO22 Mediates Polyubiquitination and Degradation of CD147 to Reverse Cisplatin Resistance of Tumor Cells.SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication.Tipping the lysine methylation balance in diseaseHistone lysine methylation dynamics: establishment, regulation, and biological impactActive modification of host inflammation by SalmonellaDNA damage emergency: cellular garbage disposal to the rescue?Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential.Cross talk between ubiquitination and demethylation.A coding single-nucleotide polymorphism in lysine demethylase KDM4A associates with increased sensitivity to mTOR inhibitors.FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine.Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase.F-box proteins in epigenetic regulation of cancer.Initial Molecular-Level Response to Artificial Selection for Increased Aerobic Metabolism Occurs Primarily through Changes in Gene Expression.CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines.A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation.Small molecule KDM4s inhibitors as anti-cancer agents.Ubiquitin Regulation: The Histone Modifying Enzyme's Story
P2860
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P2860
SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
SCF(FBXO22) regulates histone ...... iated proteasomal degradation.
@en
type
label
SCF(FBXO22) regulates histone ...... iated proteasomal degradation.
@en
prefLabel
SCF(FBXO22) regulates histone ...... iated proteasomal degradation.
@en
P2860
P356
P1476
SCF(FBXO22) regulates histone ...... diated proteasomal degradation
@en
P2093
Hui-Jun Lim
Meng-Kwang Marcus Tan
P2860
P304
P356
10.1128/MCB.05746-11
P407
P577
2011-07-18T00:00:00Z