Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.
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Microphysiometric analysis of human alpha1a-adrenoceptor expressed in Chinese hamster ovary cellsG(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtypeDual effects of muscarinic M(2) acetylcholine receptors on the synthesis of cyclic AMP in CHO cells: dependence on time, receptor density and receptor agonistsConstitutive activation of A(3) adenosine receptors by site-directed mutagenesisVENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysisSystematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassayGbeta gamma -independent constitutive association of Galpha s with SHP-1 and angiotensin II receptor AT2 is essential in AT2-mediated ITIM-independent activation of SHP-1Genetic variations in human G protein-coupled receptors: implications for drug therapy.Dominant-negative activity of an alpha(1B)-adrenergic receptor signal-inactivating point mutation.Alpha-1-adrenergic receptors: targets for agonist drugs to treat heart failure.RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility.Allosteric modulation of the M₃ muscarinic receptor by amiodarone and N-ethylamiodarone: application of the four-ligand allosteric two-state model.Role of the intracellular domains of the human FSH receptor in G(alphaS) protein coupling and receptor expressionStructure-function of alpha1-adrenergic receptors.Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).The origins of diversity and specificity in g protein-coupled receptor signalingA cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation.Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders.Constitutive activation of tethered-peptide/corticotropin-releasing factor receptor chimeras.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy.Regulated and constitutive activation of specific signalling pathways by the human S1P5 receptor.An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteinsHistamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.Up-regulation of the levels of expression and function of a constitutively active mutant of the hamster alpha1B-adrenoceptor by ligands that act as inverse agonistsDifferential response to chloroethylclonidine in blood vessels of normotensive and spontaneously hypertensive rats: role of alpha 1D- and alpha 1A-adrenoceptors in contraction.
P2860
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P2860
Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Constitutive activation of a s ...... a G protein-coupled receptor.
@en
type
label
Constitutive activation of a s ...... a G protein-coupled receptor.
@en
prefLabel
Constitutive activation of a s ...... a G protein-coupled receptor.
@en
P2093
P1476
Constitutive activation of a s ...... f a G protein-coupled receptor
@en
P2093
P304
P577
1996-01-01T00:00:00Z