Up-regulation of the levels of expression and function of a constitutively active mutant of the hamster alpha1B-adrenoceptor by ligands that act as inverse agonists
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Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutantsDetection of receptor ligands by monitoring selective stabilization of a Renilla luciferase-tagged, constitutively active mutant, G-protein-coupled receptorHow genetic errors in GPCRs affect their function: Possible therapeutic strategiesInverse agonism at heptahelical receptors: concept, experimental approach and therapeutic potential.Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.Label-free optical biosensor: a tool for G protein-coupled receptors pharmacology profiling and inverse agonists identification.New perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.Role of the fourth intracellular loop of D1-like dopaminergic receptors in conferring subtype-specific signaling properties.Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturationSingle cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors.Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists.Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2.Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.Inverse agonism and neutral antagonism at a constitutively active alpha-1a adrenoceptor.From the H(2) receptor gene to reclassification of the H(2) receptor antagonists.Effects of the inverse alpha-agonist doxazosin in allergic rhinitis.Mutations remote from the human gonadotropin-releasing hormone (GnRH) receptor-binding sites specifically increase binding affinity for GnRH II but not GnRH I: evidence for ligand-selective, receptor-active conformations.Testing for inverse agonism with constitutive receptor systems.Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity
P2860
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P2860
Up-regulation of the levels of expression and function of a constitutively active mutant of the hamster alpha1B-adrenoceptor by ligands that act as inverse agonists
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Up-regulation of the levels of ...... s that act as inverse agonists
@en
Up-regulation of the levels of ...... s that act as inverse agonists
@nl
type
label
Up-regulation of the levels of ...... s that act as inverse agonists
@en
Up-regulation of the levels of ...... s that act as inverse agonists
@nl
prefLabel
Up-regulation of the levels of ...... s that act as inverse agonists
@en
Up-regulation of the levels of ...... s that act as inverse agonists
@nl
P2093
P2860
P356
P1433
P1476
Up-regulation of the levels of ...... s that act as inverse agonists
@en
P2093
P2860
P304
P356
10.1042/BJ3250733
P407
P478
325 ( Pt 3)
P577
1997-08-01T00:00:00Z