A dyad oct-binding sequence functions as a maintenance sequence for the unmethylated state within the H19/Igf2-imprinted control region.
about
Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor.Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region.Oct4/Sox2 binding sites contribute to maintaining hypomethylation of the maternal igf2/h19 imprinting control regionNovel cis-regulatory function in ICR-mediated imprinted repression of H19The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domainsOct1 and OCA-B are selectively required for CD4 memory T cell functionInduction of DNA demethylation depending on two sets of Sox2 and adjacent Oct3/4 binding sites (Sox-Oct motifs) within the mouse H19/insulin-like growth factor 2 (Igf2) imprinted control region.The molecular function and clinical phenotype of partial deletions of the IGF2/H19 imprinting control region depends on the spatial arrangement of the remaining CTCF-binding sites.The H19 imprinting control region mediates preimplantation imprinted methylation of nearby sequences in yeast artificial chromosome transgenic mice.The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricksFunctional characterization of a testis-specific DNA binding activity at the H19/Igf2 imprinting control region.Evidence for anticipation in Beckwith-Wiedemann syndrome.Gene insulation. Part II: natural strategies in vertebrates.Molecular findings in Beckwith-Wiedemann syndrome.Epigenetic and genetic alterations of the imprinting disorder Beckwith-Wiedemann syndrome and related disorders.Beckwith-Wiedemann syndrome caused by maternally inherited mutation of an OCT-binding motif in the IGF2/H19-imprinting control region, ICR1.Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells.A novel de novo point mutation of the OCT-binding site in the IGF2/H19-imprinting control region in a Beckwith-Wiedemann syndrome patient.Fate of methylated/unmethylated H19 imprinting control region after paternal and maternal pronuclear injection.Extensive investigation of the IGF2/H19 imprinting control region reveals novel OCT4/SOX2 binding site defects associated with specific methylation patterns in Beckwith-Wiedemann syndrome
P2860
Q33932429-6EA9B808-9F5C-4D73-A7D1-B0B8169C2A64Q34463203-D9DE3A54-C42A-4976-AC23-70B79658E283Q35064058-B9C92C8F-131F-49F0-B03A-9AC32442A1BAQ35074463-6A7DBE3F-FFFC-4334-BFC4-A1262E0A8C1EQ35964289-D97F897A-2085-4C6C-9EEF-91E58C1A03D6Q36286043-0CA5254B-B55F-434F-9881-B2796BF937E6Q36481931-24B99B66-F17A-4A5B-90AA-4858C6185559Q36525863-3899F796-643D-4912-A6C4-9E6EFE5A118AQ36606998-F736F333-01D8-48B9-9CA9-490916623617Q36936127-567B0205-7E56-4BAB-8FCE-30F62246EA8FQ37056903-D9A5719D-52DC-411D-96B0-3DCAB7A2A9A2Q37317003-3F222839-34DE-43AF-B1D9-44370CD8E46FQ37811902-4DF4CA23-4C7D-4664-ACB4-327BC476B53FQ38099605-A95B8B69-95DE-4E8A-95F4-13E130B7B171Q38110380-F1C95BF1-E68F-4E4F-AAF7-5F3CF621FAC6Q40492792-D54839BE-A928-4C8E-8CBC-88F92A8DF967Q40723195-3CFAC47D-B549-4A16-8BA3-CDE6655210EAQ43807044-C161F049-E6F9-47AF-830F-CB23D528BFACQ47961972-9C923AC9-8866-4218-8D6F-E2F40B025E86Q57199288-E5E59261-BBB6-48E1-8DA0-415FF11CC79E
P2860
A dyad oct-binding sequence functions as a maintenance sequence for the unmethylated state within the H19/Igf2-imprinted control region.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
A dyad oct-binding sequence fu ...... Igf2-imprinted control region.
@en
type
label
A dyad oct-binding sequence fu ...... Igf2-imprinted control region.
@en
prefLabel
A dyad oct-binding sequence fu ...... Igf2-imprinted control region.
@en
P2093
P2860
P356
P1476
A dyad oct-binding sequence fu ...... Igf2-imprinted control region.
@en
P2093
Hiroshi Nakano
Hiroyuki Kato
Kenzo Sato
Mitsuo Oshimura
Naohiro Hori
Sayuri Hamaguchi
Toshiyuki Takeuchi
P2860
P304
27960-27967
P356
10.1074/JBC.M202280200
P407
P577
2002-05-23T00:00:00Z