p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons.
about
Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neuronsA p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regenerationOestrogen prevents cardiomyocyte apoptosis by suppressing p38α-mediated activation of p53 and by down-regulating p53 inhibition on p38β.Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease.Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.Cadmium induced p53-dependent activation of stress signaling, accumulation of ubiquitinated proteins, and apoptosis in mouse embryonic fibroblast cells.Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF.Reciprocal influence of the p53 and the hypoxic pathwaysThe Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae.Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases.NQDI-1, an inhibitor of ASK1 attenuates acute perinatal hypoxic-ischemic cerebral injury by modulating cell death.p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells.AKT mediates actinomycin D-induced p53 expression.CaMKII in the cardiovascular system: sensing redox states.p53-Dependent pathways in neurite outgrowth and axonal regeneration.Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis.p53 on the crossroad between regeneration and cancer.PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.Mechanism of hypoxia-specific cytotoxicity of procaspase-3 fused with a VHL-mediated protein destruction motif of HIF-1alpha containing Pro564.Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha.p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).Regulation of neuronal P53 activity by CXCR 4.Nuclear Localization Signal and p53 Binding Site in MAP/ERK Kinase Kinase 1 (MEKK1)Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts.p38mapk and MEK1/2 inhibition contribute to cellular oxidant injury after hypoxia.p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.Phosphodiesterase-5 inhibition abolishes neuron apoptosis induced by chronic hypoxia independently of hypoxia-inducible factor-1alpha signaling.Basic fibroblast growth factor suppresses p53 activation in the neoplastic cells of a proportion of patients with chronic lymphocytic leukaemia.Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.Low daunomycin concentrations protect colorectal cancer cells from hypoxia-induced apoptosis.HIF-1α, MDM2, CDK4, and p16 expression in ischemic fasciitis, focusing on its ischemic condition.Notch signaling and neuronal death in stroke.
P2860
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P2860
p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
p38 Mitogen-activated protein ...... on of Mdm2 and p53 in neurons.
@en
type
label
p38 Mitogen-activated protein ...... on of Mdm2 and p53 in neurons.
@en
prefLabel
p38 Mitogen-activated protein ...... on of Mdm2 and p53 in neurons.
@en
P2093
P356
P1476
p38 Mitogen-activated protein ...... on of Mdm2 and p53 in neurons.
@en
P2093
David A Greenberg
Xiao Ou Mao
Yonghua Zhu
Yunjuan Sun
Zhengui Xia
P304
22909-22914
P356
10.1074/JBC.M200042200
P407
P577
2002-04-10T00:00:00Z