p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. - Wikidata - wikimedia - TriplyDB

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

http://www.wikidata.org/entity/Q44859686

about

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression p53 and p66 proteins compete for hypoxia-inducible factor 1 alpha stabilization in young and old rat hearts exposed to intermittent hypoxia The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.Zinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1 Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death.p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta.Reciprocal influence of the p53 and the hypoxic pathways HIF-1α and HIF-2α: siblings in promoting angiogenesis of residual hepatocellular carcinoma after high-intensity focused ultrasound ablation.Chaperoning of mutant p53 protein by wild-type p53 protein causes hypoxic tumor regression.HIF-1 and p53: communication of transcription factors under hypoxia.Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF).Differential effects of hypoxia on etoposide-induced apoptosis according to the cancer cell lines Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.Mitochondrial regulation of cell survival and death during low-oxygen conditions.Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer.p53 and telomerase control rat myocardial tissue response to hypoxia and ageing.Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.Regulation of Cellular Metabolism and Hypoxia by p53.Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism.Hypoxia-induced β-catenin downregulation involves p53-dependent activation of Siah-1.CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.The eIF2alpha kinases PERK and PKR activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53.Hypoxia-regulated p53 and its effect on radiosensitivity in cancer cells.The Interaction Between Human Papillomaviruses and the Stromal Microenvironment.Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis.Transient arrest in proteasomal degradation during inhibition of translation in the unfolded protein response Reduced pulmonary function is age-dependent in the rat lung in normoxia.Differential impact of various reactive oxygen species (ROS) on HIF-1α/p53 direct interaction in SK-N-MC neuroblastoma cells Genome-wide analysis of p53 under hypoxic conditions.Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells.Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signalings.

P2860

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P2860

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

http://www.wikidata.org/entity/Q44859686

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年学术文章

@wuu

2004年学术文章

@zh

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh-hant

name

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@en

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@nl

type

label

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@en

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@nl

prefLabel

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@en

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@nl

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P1476

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.

@en

P2093

Andrew M Asham

http://www.w3.org/2001/XMLSchema#string

Cameron J Koch

http://www.w3.org/2001/XMLSchema#string

Marie Celeste Simon

http://www.w3.org/2001/XMLSchema#string

Patricia R Oprysko

http://www.w3.org/2001/XMLSchema#string

Yi Pan

http://www.w3.org/2001/XMLSchema#string

P2860

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia

Purification and characterization of hypoxia-inducible factor 1

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus.

Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt.

p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons.

Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia.

p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.

P2888

P304

4975-4983

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scholarly article

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10.1038/SJ.ONC.1207657

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29

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23

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2004-06-01T00:00:00Z

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8597025

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15107830

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P921