Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications.
about
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotidesRecent Advances in Developing Small Molecules Targeting Nucleic AcidProgress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery SystemsOligonucleotide Therapies: The Past and the PresentBioactivity of 2'-deoxyinosine-incorporated aptamer AS1411Necessity of oligonucleotide aggregation for toll-like receptor 9 activation.Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides.SL2B aptamer and folic acid dual-targeting DNA nanostructures for synergic biological effect with chemotherapy to combat colorectal cancer.Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence.A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanismAptamer photoregulation in vivoEnhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acidsBiophysical and biological properties of quadruplex oligodeoxyribonucleotidesEnzymatic synthesis of modified oligonucleotides by PEAR using Phusion and KOD DNA polymerases.Quantitative PCR analysis of DNA aptamer pharmacokinetics in mice.Disrupting the oncogenic synergism between nucleolin and Ras results in cell growth inhibition and cell deathStructure-based drug design: from nucleic acid to membrane protein targets.Quick chip assay using locked nucleic acid modified epithelial cell adhesion molecule and nucleolin aptamers for the capture of circulating tumor cellsCotinine-conjugated aptamer/anti-cotinine antibody complexes as a novel affinity unit for use in biological assays.TARGETING OF MACROPHAGE FOAM CELLS IN ATHEROSCLEROTIC PLAQUE USING OLIGONUCLEOTIDE-FUNCTIONALIZED NANOPARTICLESKinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures.Therapeutic applications of aptamers.Fully phosphorothioate-modified CpG ODN with PolyG motif inhibits the adhesion of B16 melanoma cells in vitro and tumorigenesis in vivoEffect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamerSelective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo.Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancerNucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles.Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA.Nucleic acid aptamers for targeting of shRNA-based cancer therapeutics.Grafting aptamers onto gold nanostars increases in vitro efficacy in a wide range of cancer cell types.Nucleolin inhibitor GroA triggers reduction in epidermal growth factor receptor activation: Pharmacological implication for glial scarring after spinal cord injury.Cytotoxic G-rich oligodeoxynucleotides: putative protein targets and required sequence motifTumor targeting with a (99m)Tc-labeled AS1411 aptamer in prostate tumor cells.Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma.Microflow injection potassium bioassay based on G-quadruplex DNAzyme-enhanced chemiluminescence.Multifunctional G-quadruplex aptamers and their application to protein detection.Resolution of quadruplex polymorphism by size-exclusion chromatography.Phosphorothioate oligonucleotides inhibit human immunodeficiency virus type 1 fusion by blocking gp41 core formation.Influence of loop size on the stability of intramolecular DNA quadruplexesKinetically governed polymorphism of d(G₄T₄G₃) quadruplexes in K+ solutions.
P2860
Q24793800-C01B2B49-4936-444F-83F3-426CBB794A2EQ26744202-387B9CB6-47A8-454F-ACE9-DF6C31073DA5Q26782485-B835F46A-C09B-4108-A58A-BF81DCFAB703Q27002403-AD363E7A-AA83-4294-933D-6007EC34CC2BQ28833827-1836CA6A-412F-458F-8B98-5A3A3CC7C20AQ31074458-3F802373-7BB8-46A2-8113-CFEA39167DACQ33518274-1FB8A41C-67EE-4480-BD3F-7C415C040464Q33553679-A84E37F0-7DDE-4B30-A557-EEBC82C22B59Q34058327-117391F8-43A1-47A4-88C7-308DAA203C8BQ34268342-A63E8DB3-FED7-4E0A-A8B9-FFCCC52FAF39Q34661329-001E3ED0-DBCE-4D02-BA79-B4D7B4CDF5EDQ34723597-E686CF6A-1B64-42DC-8FA4-8834683E22C6Q34966734-7496DCB9-7F4D-47B3-AA18-D86405D82E8DQ34976847-5BC002D9-CB3D-4C2D-A600-04F0AAAA396EQ34976853-7BC3F435-DEFE-42D5-B473-D59ACCCD52D9Q35005500-67D0CC42-67A1-43CA-8D43-24AF076658DBQ35127680-CC8638E5-808A-4257-8956-CE7C50F5F24AQ36117908-F0BA5D9D-D199-4C9D-A9F6-E0D81C08476FQ36301870-8EE618CA-0659-4243-A4B7-52C12CF495D8Q36359313-0F28A9EA-08E1-4F6B-B581-0E26D8F71F95Q36777809-110E2081-7DCF-4908-B1ED-AEE7E78419D1Q37038988-5DCD8FB9-FBC7-44C5-949C-D253A55D83FFQ37044950-01BFBCB8-54A5-4407-8AEB-AF8763B26ED3Q37083367-61CC1EA3-6F81-48E6-ABF7-B1278CFD4BD6Q37240103-A36CC5F3-96BF-4E84-9582-D65E46DA5BE6Q37277677-2FC7AA70-7CDB-495B-8EC5-8B155B9D0D34Q37336680-65270DF8-DC15-4260-B0DE-B4CF0DEE9659Q37444136-8865FFDF-ECC8-471F-9377-047A71A3DF55Q37586838-9CE15940-48C4-4998-A4DB-3CC847B60A7FQ37682675-97AB840F-C89E-4442-BD14-E73C8E2278C9Q38291753-C4CCB810-3D43-46BB-A23D-D80F7DE70E3AQ38300600-44F70220-5148-4612-A145-FBB698CE9229Q38301100-4F865B72-C685-49A7-A70F-B71FAE64B0D0Q38303924-1986D895-2552-43C9-B01F-EAD71C2625F5Q38306923-A809E85C-A53E-4A9F-94AE-0271D45493BCQ38358445-BD393237-19E0-4C53-8637-0279BFD184B9Q38426871-A64BE1C4-8050-49D1-9ADB-0525E7C68228Q40298802-C8EA5E2F-6ED8-46D3-AA72-DDD9A317922CQ40899964-47A63155-F8C7-40DC-BEEC-67FEFE55BD19Q42128076-4497B7CF-4B26-449C-817B-ADFA6E7655DF
P2860
Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Antiproliferative activity of ...... kbone and sugar modifications.
@en
type
label
Antiproliferative activity of ...... kbone and sugar modifications.
@en
prefLabel
Antiproliferative activity of ...... kbone and sugar modifications.
@en
P2093
P356
P1433
P1476
Antiproliferative activity of ...... ckbone and sugar modifications
@en
P2093
Donald M Miller
John O Trent
Paula J Bates
Shelia D Thomas
Virna Dapić
P304
P356
10.1021/BI0119520
P407
P577
2002-03-01T00:00:00Z