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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

http://www.wikidata.org/entity/Q34966734

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Quadruplex DNA: sequence, topology and structure Highly prevalent putative quadruplex sequence motifs in human DNA Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation Interactions of the G quartet forming semaphorin 3F RNA with the RGG box domain of the fragile X protein family Kinetics of tetramolecular quadruplexes The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand.Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems Conformational changes in DNA upon ligand binding monitored by circular dichroism Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA General cell-binding activity of intramolecular G-quadruplexes with parallel structure Intramolecular DNA quadruplexes with different arrangements of short and long loops Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization.Structural studies on LNA quadruplexes.Capture and identification of proteins that bind to a GGA-rich sequence from the ERBB2 gene promoter region.Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides.Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium.Alternative DNA structure formation in the mutagenic human c-MYC promoter.An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase.Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeats Structure of the biologically relevant G-quadruplex in the c-MYC promoter.Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence.Thermodynamic stability and folding kinetics of the major G-quadruplex and its loop isomers formed in the nuclease hypersensitive element in the human c-Myc promoter: effect of loops and flanking segments on the stability of parallel-stranded intram A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism Engineering the quadruplex fold: nucleoside conformation determines both folding topology and molecularity in guanine quadruplexes.NMR solution structures of LNA (locked nucleic acid) modified quadruplexes.Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids Quantitative PCR analysis of DNA aptamer pharmacokinetics in mice.Kinetic partitioning modulates human telomere DNA G-quadruplex structural polymorphism.Structure-based drug design: from nucleic acid to membrane protein targets.In vitro selection of DNA-based aptamers that exhibit RNA-like conformations using a chimeric oligonucleotide library that contains two different xeno-nucleic acids.Sites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitro A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target.POT1-TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism.Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative.

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

http://www.wikidata.org/entity/Q34966734

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2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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Nucleic Acids Research

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Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

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P2093

Jemma Peberdy

http://www.w3.org/2001/XMLSchema#string

John O Trent

http://www.w3.org/2001/XMLSchema#string

Paula J Bates

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Rachel Marrington

http://www.w3.org/2001/XMLSchema#string

Vedra Abdomerović

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Virna Dapić

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P2860

Crystal structure of parallel quadruplexes from human telomeric DNA

Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4))

An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex

Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat

Solution structure of the Na+ form of the dimeric guanine quadruplex [d(G3T4G3)]2

Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution

Solution structure of the Oxytricha telomeric repeat d[G4(T4G4)3] G-tetraplex

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2097-2107

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scholarly article

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10.1093/NAR/GKG316

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8

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31

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274133428

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