Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel.
about
Recent progress in structure-based anti-influenza drug designStructure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virusNew small-molecule drug design strategies for fighting resistant influenza ATwo birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicineAn assay suitable for high throughput screening of anti-influenza drugsFlipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesDiscovery of Highly Potent Inhibitors Targeting the Predominant Drug-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.Antiviral strategies against influenza virus: towards new therapeutic approaches.Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses.An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.Isocyanides as Influenza A Virus Subtype H5N1 Wild-Type M2 Channel Inhibitors.The 7-aza-norbornane nucleus of epibatidine: 7-aza-bicyclo-[2.2.1]heptan-7-ium chloride.3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus.Ru(ii)-Pheox-catalyzed Si-H insertion reaction: construction of enantioenriched carbon and silicon centers.Chemoselective Silylative Reduction of Conjugated Nitriles under Metal-Free Catalytic Conditions: β-Silyl Amines and Enamines.Synthesis, Reactivity, Functionalization, and ADMET Properties of Silicon-Containing Nitrogen Heterocycles.
P2860
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P2860
Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Exploring organosilane amines ...... nza a virus M2 proton channel.
@en
type
label
Exploring organosilane amines ...... nza a virus M2 proton channel.
@en
prefLabel
Exploring organosilane amines ...... nza a virus M2 proton channel.
@en
P2093
P2860
P356
P1476
Exploring organosilane amines ...... nza a virus M2 proton channel.
@en
P2093
Chunlong Ma
Lawrence H Pinto
Robert A Lamb
P2860
P304
13844-13847
P356
10.1021/JA2050666
P407
P577
2011-08-12T00:00:00Z