Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain.
about
The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivatorsPOU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response elementTTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiationP-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland developmentThe prolactin gene: a paradigm of tissue-specific gene regulation with complex temporal transcription dynamicsFunctional interaction between Oct-1 and retinoid X receptorSelective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoterPit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoterA Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoterSelective inhibition of prolactin gene transcription by the ETS-2 repressor factor.Combined pituitary hormone deficiency: current and future status.Atypical binding of the neuronal POU protein N-Oct3 to noncanonical DNA targets. Implications for heterodimerization with HNF-3 beta.Research resource: A genome-wide study identifies potential new target genes for POU1F1Functionally distinct monomers and trimers produced by a viral oncoprotein.Distinct variant DNA-binding sites determine cell-specific autoregulated expression of the Drosophila POU domain transcription factor drifter in midline glia or trachea.A unique transactivation sequence motif is found in the carboxyl-terminal domain of the single-strand-binding protein FBPA dimer-specific function of the transcription factor NFATp.The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domainExpression of the synaptotagmin I gene is enhanced by binding of the pituitary-specific transcription factor, POU1F1.Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation.Glucocorticoid repression of the mouse gonadotropin-releasing hormone gene is mediated by promoter elements that are recognized by heteromeric complexes containing glucocorticoid receptor.Expression of the gene for the POU domain transcription factor Tst-1/Oct6 is regulated by an estrogen-dependent enhancer.C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter.Ultrastructural and immunoelectron microscopic study of three unusual plurihormonal pituitary adenomas.The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropin-releasing hormone distal negative glucocorticoid response element.An activation function in Pit-1 required selectively for synergistic transcription.Molecular characterization of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1.Ras signaling and transcriptional synergy at a flexible Ets-1/Pit-1 composite DNA element is defined by the assembly of selective activation domains.Nuclear factor 1 regulates the distal silencer of the human PIT1/GHF1 gene.The Pit-1 homeodomain and beta-domain interact with Ets-1 and modulate synergistic activation of the rat prolactin promoter.Thyroid hormone receptor beta2 promoter activity in pituitary cells is regulated by Pit-1.AP-1 and Oct-1 transcription factors down-regulate the expression of the human PIT1/GHF1 gene.Cloning of the full length pig PIT1 (POU1F1) CDNA and a novel alternative PIT1 transcript, and functional studies of their encoded proteins.
P2860
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P2860
Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Pit-1 binding to specific DNA ...... sine-dependent synergy domain.
@en
type
label
Pit-1 binding to specific DNA ...... sine-dependent synergy domain.
@en
prefLabel
Pit-1 binding to specific DNA ...... sine-dependent synergy domain.
@en
P2093
P356
P1433
P1476
Pit-1 binding to specific DNA ...... sine-dependent synergy domain.
@en
P2093
P304
P356
10.1101/GAD.9.16.1992
P577
1995-08-01T00:00:00Z