Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase. - Wikidata - wikimedia - TriplyDB

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.

http://www.wikidata.org/entity/Q38292943

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Gene function in early mouse embryonic stem cell differentiation.RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization Leupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cells Leupaxin is similar to paxillin in focal adhesion targeting and tyrosine phosphorylation but has distinct roles in cell adhesion and spreading.NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141 Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6 Paxillin contracts the osteoclast cytoskeleton Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS.Minimal features of paxillin that are required for the tyrosine phosphorylation of focal adhesion kinase Transformation by bovine papillomavirus type 1 E6 requires paxillin.Human papillomavirus E6 regulates the cytoskeleton dynamics of keratinocytes through targeted degradation of p53 Erk1/2 MAPK and caldesmon differentially regulate podosome dynamics in A7r5 vascular smooth muscle cells.TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over time.Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells.Activation of PKCβII by PMA facilitates enhanced epithelial wound repair through increased cell spreading and migration.Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation.Interaction between mDia1 and ROCK in Rho-induced migration and adhesion of human dental pulp cells.Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle Paxillin: a crossroad in pathological cell migration Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression.Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing.Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.Deregulation of focal adhesion formation and cytoskeletal tension due to loss of A-type lamins.Myoferlin depletion elevates focal adhesion kinase and paxillin phosphorylation and enhances cell-matrix adhesion in breast cancer cells.Interaction of Pyk2 and PTP-PEST with leupaxin in prostate cancer cells.Multiple paxillin binding sites regulate FAK function.Dasatinib inhibits actin fiber reorganization and promotes endothelial cell permeability through RhoA-ROCK pathway Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis.Tenascin-C blocks cell-cycle progression of anchorage-dependent fibroblasts on fibronectin through inhibition of syndecan-4.Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration.

P2860

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P2860

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.

http://www.wikidata.org/entity/Q38292943

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

@wuu

2002年学术文章

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2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

2002年學術文章

@zh

2002年學術文章

@zh-hant

name

Paxillin null embryonic stem c ...... tion of focal adhesion kinase.

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type

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Paxillin null embryonic stem c ...... tion of focal adhesion kinase.

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Paxillin null embryonic stem c ...... tion of focal adhesion kinase.

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Paxillin null embryonic stem c ...... tion of focal adhesion kinase.

@en

P2093

Joanna Bohl

http://www.w3.org/2001/XMLSchema#string

Ramon Wade

http://www.w3.org/2001/XMLSchema#string

Scott Vande Pol

http://www.w3.org/2001/XMLSchema#string

P2860

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton

Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif

Leupaxin is a novel LIM domain protein that forms a complex with PYK2

A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.

An ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organization

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts.

Paxillin: a new vinculin-binding protein present in focal adhesions

P2888

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96-107

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10.1038/SJ.ONC.1205013

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1

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21

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1031233256

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11791180

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phosphorylation