G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
about
KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.Increases in intracellular calcium triggered by channelrhodopsin-2 potentiate the response of metabotropic glutamate receptor mGluR7Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells.Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channelNew mechanism for voltage induced charge movement revealed in GPCRs--theory and experimentsSignal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channelModulation of midbrain dopamine neurotransmission by serotonin, a versatile interaction between neurotransmitters and significance for antipsychotic drug action.Voltage affects the dissociation rate constant of the m2 muscarinic receptor.Differential roles of Arabidopsis heterotrimeric G-protein subunits in modulating cell division in roots.G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK)Molecular mechanisms of go signalingHL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.Stargazin modulates neuronal voltage-dependent Ca(2+) channel Ca(v)2.2 by a Gbetagamma-dependent mechanism.Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.Graded contribution of the Gbeta gamma binding domains to GIRK channel activation.Plants: the latest model system for G-protein researchSingle channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation.Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold librariesCoordination of membrane excitability through a GIRK1 signaling complex in the atria.Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics.N-terminal tyrosine residues within the potassium channel Kir3 modulate GTPase activity of Galphai.A novel fast mechanism for GPCR-mediated signal transduction--control of neurotransmitter release.Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.Gi protein activation in intact cells involves subunit rearrangement rather than dissociationTwo distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunitsActivated G protein α s subunits increase the ethanol sensitivity of human glycine receptorsStructural basis for modulation of gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by i/o-family G protein α subunit (Gαi/o).The role of inhibitory heterotrimeric G proteins in the control of in vivo heart rate dynamics.A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.The TRPM1 channel in ON-bipolar cells is gated by both the α and the βγ subunits of the G-protein GoKir2.4 surface expression and basal current are affected by heterotrimeric G-proteins.Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress.Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release.Abscisic acid regulation of guard-cell K+ and anion channels in Gbeta- and RGS-deficient Arabidopsis linesRegulation of neuronal ion channels via P2Y receptors.Addictive drugs modulate GIRK-channel signaling by regulating RGS proteinsSupramolecular assemblies and localized regulation of voltage-gated ion channels.
P2860
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P2860
G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
@en
type
label
G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
@en
prefLabel
G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
@en
P2093
P1433
P1476
G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
@en
P2093
Carmen W Dessauer
Dalia Varon
Nathan Dascal
Sagit Peleg
Tatiana Ivanina
P356
10.1016/S0896-6273(01)00567-0
P407
P577
2002-01-01T00:00:00Z