A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9.
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Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycansMolecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteinsThe structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor designLarge-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanismsStructural implications of Siglec-5-mediated sialoglycan recognitionSiglecs as sensors of self in innate and adaptive immune responsesSiglecs and immune regulationHigh resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec familyHuman natural killer cell receptors: insights into their molecular function and structureSialic acid-binding immunoglobulin-like lectin 7 mediates selective recognition of sialylated glycans expressed on Campylobacter jejuni lipooligosaccharidesMouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligandNegative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9Glycan array screening reveals a candidate ligand for Siglec-8Multivalent Interactions of Human Primary Amine Oxidase with the V and C22 Domains of Sialic Acid-Binding Immunoglobulin-Like Lectin-9 Regulate Its Binding and Amine Oxidase ActivityIdentification of an essential sequence for dihydroceramide C-4 hydroxylase activity of mouse DES2Chemoenzymatic synthesis of GD3 oligosaccharides and other disialyl glycans containing natural and non-natural sialic acidsMUC16 (CA125): tumor biomarker to cancer therapy, a work in progressChemoenzymatic synthesis of α2-3-sialylated carbohydrate epitopes.Engagement of Siglec-7 receptor induces a pro-inflammatory response selectively in monocytes.Determination of major sialylated N-glycans and identification of branched sialylated N-glycans that dynamically change their content during development in the mouse cerebral cortex.High affinity sialoside ligands of myelin associated glycoprotein.Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-EGerminal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation.The mucin MUC16 (CA125) binds to NK cells and monocytes from peripheral blood of women with healthy pregnancy and preeclampsia.A new self: MHC-class-I-independent natural-killer-cell self-tolerance.Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8Basic and clinical immunology of SiglecsGangliosides in cell recognition and membrane protein regulationSialic acid-binding Ig-like lectin-7 interacts with HIV-1 gp120 and facilitates infection of CD4pos T cells and macrophages.Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact.Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance.Host Immune Responses in HIV-1 Infection: The Emerging Pathogenic Role of Siglecs and Their Clinical Correlates.Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes.Nanoengineered glycan sensors enabling native glycoprofiling for medicinal applications: towards profiling glycoproteins without labeling or liberation steps.Disialic, oligosialic and polysialic acids: distribution, functions and related disease.Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b.Campylobacter jejuni lipooligosaccharides modulate dendritic cell-mediated T cell polarization in a sialic acid linkage-dependent manner.Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein.Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness.Viewing Siglecs through the lens of tumor immunology.
P2860
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P2860
A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
A small region of the natural ...... s. A comparison with Siglec-9.
@en
type
label
A small region of the natural ...... s. A comparison with Siglec-9.
@en
prefLabel
A small region of the natural ...... s. A comparison with Siglec-9.
@en
P2093
P2860
P356
P1476
A small region of the natural ...... s. A comparison with Siglec-9.
@en
P2093
Magnus S Alphey
Takane Teranishi
Toshiyuki Yamaji
Yasuhiro Hashimoto
P2860
P304
P356
10.1074/JBC.M110146200
P407
P577
2001-12-10T00:00:00Z