The Ras-related GTP-binding protein, Rab1B, regulates early steps in exocytic transport and processing of beta-amyloid precursor protein.
about
Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cellsMutant Rab24 GTPase is targeted to nuclear inclusions.β-Amyloid: the key peptide in the pathogenesis of Alzheimer's diseaseTrafficking regulation of proteins in Alzheimer's diseasePITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant SecretionIIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3A new functional screening system for identification of regulators for the generation of amyloid beta-protein.Dysregulation of protein trafficking in neurodegeneration.Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading proteaseDefects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function.Regulation of the trafficking and function of G protein-coupled receptors by Rab1 GTPase in cardiomyocytes.Analysis of Rab1 function in cardiomyocyte growth.Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptorsIdentification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling.Killing of cancer cells by the photoactivatable protein kinase C inhibitor, calphostin C, involves induction of endoplasmic reticulum stress.Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein.Simvastatin inhibits protein isoprenylation in the brain.Statins reduce amyloid-beta production through inhibition of protein isoprenylation.Regulation of the cell surface expression and function of angiotensin II type 1 receptor by Rab1-mediated endoplasmic reticulum-to-Golgi transport in cardiac myocytes.Distinct pathways for the trafficking of angiotensin II and adrenergic receptors from the endoplasmic reticulum to the cell surface: Rab1-independent transport of a G protein-coupled receptor.Proteomics of rat liver Golgi complex: minor proteins are identified through sequential fractionation.Rab24 is an atypical member of the Rab GTPase family. Deficient GTPase activity, GDP dissociation inhibitor interaction, and prenylation of Rab24 expressed in cultured cells.Association of Rab1B with GDP-dissociation inhibitor (GDI) is required for recycling but not initial membrane targeting of the Rab protein.Intracellular transport and maturation of nascent low density lipoprotein receptor is blocked by mutation in the Ras-related GTP-binding protein, RAB1B.Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neuronsConsequences of Rab GTPase dysfunction in genetic or acquired human diseases.Conserved Oligomeric Golgi and Neuronal Vesicular Trafficking.Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.Rha1, an Arabidopsis Rab5 homolog, plays a critical role in the vacuolar trafficking of soluble cargo proteins
P2860
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P2860
The Ras-related GTP-binding protein, Rab1B, regulates early steps in exocytic transport and processing of beta-amyloid precursor protein.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
The Ras-related GTP-binding pr ...... eta-amyloid precursor protein.
@en
type
label
The Ras-related GTP-binding pr ...... eta-amyloid precursor protein.
@en
prefLabel
The Ras-related GTP-binding pr ...... eta-amyloid precursor protein.
@en
P2093
P2860
P356
P1476
The Ras-related GTP-binding pr ...... eta-amyloid precursor protein.
@en
P2093
P2860
P304
10982-10989
P356
10.1074/JBC.270.18.10982
P407
P577
1995-05-01T00:00:00Z