Circulating succinate is elevated in rodent models of hypertension and metabolic disease.
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Metabolic Inflammation-Differential Modulation by Dietary ConstituentsMitochondria-controlled signaling mechanisms of brain protection in hypoxiaGPR91: expanding the frontiers of Krebs cycle intermediatesMetabolic reprogramming in macrophages and dendritic cells in innate immunitySuccinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney.Succinate is an inflammatory signal that induces IL-1β through HIF-1α.SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.Mitochondrial polymorphisms in rat genetic models of hypertension.Calcium signals in the nucleus accumbens: activation of astrocytes by ATP and succinateThe succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditionsMetabolic control of renin secretionThe Drosophila surface glia transcriptome: evolutionary conserved blood-brain barrier processesSuccinate causes pathological cardiomyocyte hypertrophy through GPR91 activation.Maintenance of homeostasis in the aging hypothalamus: the central and peripheral roles of succinate.Metabolic reprograming of mononuclear phagocytes in progressive multiple sclerosis.Identification of lead compounds for (99m)Tc and (18)F GPR91 radiotracersTumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondriaActivation of HIF-1α (hypoxia inducible factor-1α) prevents dry eye-induced acinar cell death in the lacrimal glandIdentification and pharmacological characterization of succinate receptor agonists.Regulation of Vascular and Renal Function by Metabolite ReceptorsMetabolomic profiling reveals a role for caspase-2 in lipoapoptosisAnatomical profiling of G protein-coupled receptor expressionActivation of the succinate receptor GPR91 in macula densa cells causes renin release.GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.Renal and cardiovascular sensory receptors and blood pressure regulation.Unsung renal receptors: orphan G-protein-coupled receptors play essential roles in renal development and homeostasis.G protein-coupled receptor 91 signaling in diabetic retinopathy and hypoxic retinal diseases.GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice.Activation of astroglial calcium signaling by endogenous metabolites succinate and gamma-hydroxybutyrate in the nucleus accumbens.Effects of monobutyrin and tributyrin on liver lipid profile, caecal microbiota composition and SCFA in high-fat diet-fed rats.Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91.Expression of sodium-dependent dicarboxylate transporter 1 (NaDC1/SLC13A2) in normal and neoplastic human kidney.Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota.Plasma succinate is a predictor of mortality in critically injured patients.Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.Multiple faces of succinate beyond metabolism in bloodSuccinate as a Regulator of Hepatic Stellate Cells in Liver Fibrosis
P2860
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P2860
Circulating succinate is elevated in rodent models of hypertension and metabolic disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Circulating succinate is elevated in rodent models of hypertension and metabolic disease.
@en
type
label
Circulating succinate is elevated in rodent models of hypertension and metabolic disease.
@en
prefLabel
Circulating succinate is elevated in rodent models of hypertension and metabolic disease.
@en
P2093
P1476
Circulating succinate is elevated in rodent models of hypertension and metabolic disease
@en
P2093
Gregory M Preston
Michael A Tones
Nalini Sadagopan
Terry Major
P304
P356
10.1016/J.AMJHYPER.2007.05.010
P577
2007-11-01T00:00:00Z