The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein.
about
START lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factorsCrystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domainIntracellular cholesterol transportSTARD4 abundance regulates sterol transport and sensingInter-organelle ER-endolysosomal contact sites in metabolism and disease across evolutionTRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell MigrationTargeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolismMLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 proteinDiversity of raft-like domains in late endosomesSTARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sitesFunctional characterization of the MENTAL domain.MLN64 is involved in actin-mediated dynamics of late endocytic organelles.Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1MENTHO, a MLN64 homologue devoid of the START domain.Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.StAR overexpression decreases serum and tissue lipids in apolipoprotein E-deficient mice.Steroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system.Early steps in steroidogenesis: intracellular cholesterol trafficking.MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding siteInsights into the mechanisms of sterol transport between organelles.Sterol transport in yeast and the oxysterol binding protein homologue (OSH) familyNon-vesicular sterol transport in cells.The Drosophila gene Start1: a putative cholesterol transporter and key regulator of ecdysteroid synthesis.Lipid imbalance in the neurological disorder, Niemann-Pick C disease.Late endocytic multivesicular bodies intersect the chlamydial inclusion in the absence of CD63.Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.Intracellular sterol dynamicsCholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function.Membrane Contact Sites: Complex Zones for Membrane Association and Lipid Exchange.Cellular Cholesterol Homeostasis in Alzheimer's Disease.Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages.Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.Involvement of Niemann-Pick type C2 protein in hematopoiesis regulation.Metastatic lymph node 64 (MLN64), a gene overexpressed in breast cancers, is regulated by Sp/KLF transcription factors.Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1.Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotypeThe potential function of steroid sulphatase activity in steroid production and steroidogenic acute regulatory protein expression.MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content.
P2860
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P2860
The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
The steroidogenic acute regula ...... l cholesterol-binding protein.
@en
type
label
The steroidogenic acute regula ...... l cholesterol-binding protein.
@en
prefLabel
The steroidogenic acute regula ...... l cholesterol-binding protein.
@en
P2093
P2860
P356
P1476
The steroidogenic acute regula ...... al cholesterol-binding protein
@en
P2093
Chenard MP
Gruenberg J
Stoeckel ME
Wendling C
P2860
P304
P356
10.1074/JBC.M006279200
P407
P577
2000-10-26T00:00:00Z