Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I.
about
A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteinsThe retrotranslocation protein Derlin-1 binds peptide:N-glycanase to the endoplasmic reticulumDissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatinThe pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ERTURAN and EVAN mediate pollen tube reception in Arabidopsis Synergids through protein glycosylationEDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimmingTay-Sachs disease mutations in HEXA target the α chain of hexosaminidase A to endoplasmic reticulum-associated degradationStructure-function analysis of STRUBBELIG, an Arabidopsis atypical receptor-like kinase involved in tissue morphogenesisProbing for membrane domains in the endoplasmic reticulum: retention and degradation of unassembled MHC class I molecules.Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexinEndoplasmic reticulum-associated N-glycan degradation of cold-upregulated glycoproteins in response to chilling stress in Arabidopsis.Marker-trait association analysis of frost tolerance of 672 worldwide pea (Pisum sativum L.) collections.OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation.Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradationMutations of an alpha1,6 mannosyltransferase inhibit endoplasmic reticulum-associated degradation of defective brassinosteroid receptors in Arabidopsis.Mixed-disulfide folding intermediates between thyroglobulin and endoplasmic reticulum resident oxidoreductases ERp57 and protein disulfide isomerase.Synthesis, Processing, and Function of N-glycans in N-glycoproteins.The C-terminal T peptide of acetylcholinesterase enhances degradation of unassembled active subunits through the ERAD pathwaySearch and destroy: ER quality control and ER-associated protein degradation.Evolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis.Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradationCellular response to endoplasmic reticulum stress: a matter of life or death.Cotranslational endoplasmic reticulum assembly of FcepsilonRI controls the formation of functional IgE-binding receptors.Thyroglobulin From Molecular and Cellular Biology to Clinical Endocrinology.The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species.The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation).Deficiency of ATP2C1, a Golgi ion pump, induces secretory pathway defects in endoplasmic reticulum (ER)-associated degradation and sensitivity to ER stress.Oxidoreductase interactions include a role for ERp72 engagement with mutant thyroglobulin from the rdw/rdw rat dwarf.UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum.Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiterControl of the pattern-recognition receptor EFR by an ER protein complex in plant immunity.Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.Iminosugar antivirals: the therapeutic sweet spot.Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins.Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications.Misfolded endoplasmic reticulum retained subunits cause degradation of wild-type subunits of arylsulfatase A heteromers.Protein disulfide isomerase-like proteins play opposing roles during retrotranslocationTwo distinct pathways for cyclooxygenase-2 protein degradation.alphaIIbbeta3 biogenesis is controlled by engagement of alphaIIb in the calnexin cycle via the N15-linked glycan.Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.
P2860
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P2860
Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Endoplasmic reticulum (ER)-ass ...... nhibition of ER mannosidase I.
@en
type
label
Endoplasmic reticulum (ER)-ass ...... nhibition of ER mannosidase I.
@en
prefLabel
Endoplasmic reticulum (ER)-ass ...... nhibition of ER mannosidase I.
@en
P2093
P2860
P356
P1476
Endoplasmic reticulum (ER)-ass ...... nhibition of ER mannosidase I.
@en
P2093
P2860
P304
40757-40764
P356
10.1074/JBC.M001073200
P407
P577
2000-12-01T00:00:00Z