Two distinct pathways for cyclooxygenase-2 protein degradation. - Wikidata - wikimedia - TriplyDB

Two distinct pathways for cyclooxygenase-2 protein degradation.

Two distinct pathways for cyclooxygenase-2 protein degradation.

http://www.wikidata.org/entity/Q40023431

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Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer 2-hydroxy arachidonic acid: a new non-steroidal anti-inflammatory drug Cyclooxygenases: structural and functional insights.A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide.Inducible nitric oxide synthase gene deletion exaggerates MAPK-mediated cyclooxygenase-2 induction by inflammatory stimuli The response of human macrophages to β-glucans depends on the inflammatory milieu.Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration.PharmGKB summary: very important pharmacogene information for PTGS2.A cyclooxygenase-2-dependent prostaglandin E2 biosynthetic system in the Golgi apparatus Prophylactic, prandial rofecoxib treatment lacks efficacy against acute PTZ-induced seizure generation and kindling acquisition.Protein Phosphatase 2A in Lipopolysaccharide-Induced Cyclooxygenase-2 Expression in Murine Lymphatic Endothelial Cells.Induction of cell cycle arrest and apoptosis with downregulation of Hsp90 client proteins and histone modification by 4β-hydroxywithanolide E isolated from Physalis peruviana.Cyclooxygenase Isoform Exchange Blocks Brain-Mediated Inflammatory Symptoms Different Fatty Acids Compete with Arachidonic Acid for Binding to the Allosteric or Catalytic Subunits of Cyclooxygenases to Regulate Prostanoid Synthesis.Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry.Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2.Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers.Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.Two pathways for cyclooxygenase-2 protein degradation in vivo Development of prostaglandin endoperoxide synthase expression in the ovine fetal central nervous system and pituitary.The ubiquitin-proteasome pathway and endothelial (dys)function.Cyclooxygenase 2: its regulation, role and impact in airway inflammation.Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts.WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-inflammatory properties via MKP-1 in LPS-stimulated RAW264.7 macrophages.Prostaglandin EP1 receptor down-regulates expression of cyclooxygenase-2 by facilitating its proteasomal degradation 2-Methoxy-5-amino-N-hydroxybenzamide, a derivative of mesalamine, inhibits colon cancer cell growth through cyclo-oxygenase-2-dependent and -independent mechanisms.Rapid degradation of cyclooxygenase-1 and hematopoietic prostaglandin D synthase through ubiquitin-proteasome system in response to intracellular calcium level Overexpression of cyclooxygenase-2 in NCI-H292 human alveolar epithelial carcinoma cells: roles of p38 MAPK, ERK-1/2, and PI3K/PKB signaling proteins.IL-17A increases TNF-α-induced COX-2 protein stability and augments PGE2 secretion from airway smooth muscle cells: impact on β2 -adrenergic receptor desensitization.A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity.Down-regulation of cyclooxygenase-2 by the carboxyl tail of the angiotensin II type 1 receptor.N-glycosylation site occupancy in human prostaglandin H synthases expressed in Pichia pastoris.Apoptosis signal-regulating kinase 1 in peptidoglycan-induced COX-2 expression in macrophages.Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit.Flipping the cyclooxygenase (Ptgs) genes reveals isoform-specific compensatory functions.Cyclooxygenase 2: protein-protein interactions and posttranslational modifications.

P2860

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P2860

Two distinct pathways for cyclooxygenase-2 protein degradation.

http://www.wikidata.org/entity/Q40023431

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Two distinct pathways for cyclooxygenase-2 protein degradation.

@en

type

label

Two distinct pathways for cyclooxygenase-2 protein degradation.

@en

prefLabel

Two distinct pathways for cyclooxygenase-2 protein degradation.

@en

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Journal of Biological Chemistry

P1476

Two distinct pathways for cyclooxygenase-2 protein degradation.

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P2093

Chong Yuan

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Clair E Harris

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Inseok Song

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Ranjinder S Sidhu

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Toshiya Arakawa

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William L Smith

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P2860

Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation.

Yos9p detects and targets misfolded glycoproteins for ER-associated degradation.

Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure.

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

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8611-8623

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10.1074/JBC.M710137200

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13

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283

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2008-01-18T00:00:00Z

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18203712

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