Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.
about
Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activityRegulation of glucose metabolism from a liver-centric perspectiveTribbles-1: a novel regulator of hepatic lipid metabolism in humansTranscriptional regulation of hepatic lipogenesisPathway-selective insulin resistance and metabolic disease: the importance of nutrient fluxGenetically modified mouse models for the study of nonalcoholic fatty liver diseaseEnergy metabolism in the liverCurcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytesMondo/ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in DrosophilaObesity and non-alcoholic fatty liver disease: Disparate associations among Asian populationsImmune surveillance of liver cancer in non-alcoholic fatty liver disease: excess lipids cause CD4 T-cells loss and promote hepatocellular carcinoma developmentGlucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cellsAtorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase AMondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signalingFructose: it's "alcohol without the buzz".miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway.Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP.Deficiency of the transcriptional repressor B cell lymphoma 6 (Bcl6) is accompanied by dysregulated lipid metabolismTime-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in ratsA new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats.Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity.Molecular pathways in non-alcoholic fatty liver disease.Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression.Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?Pleiotropic genes for metabolic syndrome and inflammationThyroid hormone receptor beta (TRbeta) and liver X receptor (LXR) regulate carbohydrate-response element-binding protein (ChREBP) expression in a tissue-selective manner.Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance.Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signalingAlpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice.Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosisChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cellsFructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet.Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.Intersection of the unfolded protein response and hepatic lipid metabolismPPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle.Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids.Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetesDifferential effects of krill oil and fish oil on the hepatic transcriptome in miceFatty acid synthase and liver triglyceride metabolism: housekeeper or messenger?Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.
P2860
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P2860
Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Liver-specific inhibition of C ...... ulin resistance in ob/ob mice.
@en
type
label
Liver-specific inhibition of C ...... ulin resistance in ob/ob mice.
@en
prefLabel
Liver-specific inhibition of C ...... ulin resistance in ob/ob mice.
@en
P2093
P50
P356
P1433
P1476
Liver-specific inhibition of C ...... sulin resistance in ob/ob mice
@en
P2093
Fadila Benhamed
Isabelle Hainault
Jason R B Dyck
Jean Girard
Véronique Fauveau
P304
P356
10.2337/DB06-0200
P407
P577
2006-08-01T00:00:00Z