A robust small-molecule microarray platform for screening cell lysates.
about
A small molecule that binds Hedgehog and blocks its signaling in human cellsTechniques for molecular imaging probe designIdentification of a peptoid inhibitor of the proteasome 19S regulatory particle.Interrogating yeast surface-displayed human proteome to identify small molecule-binding proteins.Small-molecule microarrays as tools in ligand discovery.Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II.Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support.Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic HedgehogSeamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial librariesBinding affinity and kinetic analysis of targeted small molecule-modified nanoparticles.The Listeria monocytogenes σB regulon and its virulence-associated functions are inhibited by a small moleculeSmall-molecule modulators of the Sonic Hedgehog signaling pathway.Simultaneous measurement of 10,000 protein-ligand affinity constants using microarray-based kinetic constant assays.A small molecule that binds and inhibits the ETV1 transcription factor oncoproteinSmall molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles.Small-Molecule Library Synthesis on Silicon-Functionalized SynPhase LanternsBio-inspired voltage-dependent calcium channel blockersA HaloTag-based small molecule microarray screening methodology with increased sensitivity and multiplex capabilities.Catalytic in vivo protein knockdown by small-molecule PROTACs.Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays.A versatile method for functionalizing surfaces with bioactive glycans.Proteins from an unevolved library of de novo designed sequences bind a range of small molecules.Recent discoveries and applications involving small-molecule microarraysDeveloping an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate ChemistryScreening of Small Molecule Microarrays for Ligands Targeted to the Extracellular Epitopes of Living Cells.Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays.Neurobiological applications of small molecule screening.Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.Protein microarrays for genome-wide posttranslational modification analysis.Use of Microarrays as a High-Throughput Platform for Label-Free Biosensing.The Emerging Role of RNA as a Therapeutic Target for Small Molecules.A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2.A hydrogel-based versatile screening platform for specific biomolecular recognition in a well plate format.A solvation-based screening approach for metabolite arrays.The Expanding World of Small Molecule Microarrays.Automatic Spot Identification Method for High Throughput Surface Plasmon Resonance Imaging Analysis
P2860
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P2860
A robust small-molecule microarray platform for screening cell lysates.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A robust small-molecule microarray platform for screening cell lysates.
@en
type
label
A robust small-molecule microarray platform for screening cell lysates.
@en
prefLabel
A robust small-molecule microarray platform for screening cell lysates.
@en
P2093
P1476
A robust small-molecule microarray platform for screening cell lysates.
@en
P2093
Angela N Koehler
David Barnes-Seeman
Donna S Neuberg
James E Bradner
Jasmeet Dhaliwal
Jay L Duffner
John P Shen
Kristen E Stevenson
Olivia M McPherson
Paul Nghiem
P304
P356
10.1016/J.CHEMBIOL.2006.03.004
P577
2006-05-01T00:00:00Z