about
In vitro selection, characterization, and application of deoxyribozymes that cleave RNACatalytic DNAs as potential therapeutic agents and sequence-specific molecular tools to dissect biological function.A novel replicating circular DNAzyme.Urokinase plasminogen activator system as a potential target for cancer therapy.Systematic analysis of the role of target site accessibility in the activity of DNA enzymes.Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme.RNA cleaving '10-23' DNAzymes with enhanced stability and activity.DNA enzymes as potential therapeutics: towards clinical application of 10-23 DNAzymes.Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sitesSelective DNAzyme-mediated cleavage of AChR mutant transcripts by targeting the mutation site or through mismatches in the binding arm.Coarse-Grained Brownian Dynamics Simulations of the 10-23 DNAzyme.Recapitulation of the hairless mouse phenotype using catalytic oligonucleotides: implications for permanent hair removal.
P2860
Q24817034-39161966-4A03-4373-828C-C255ABD60C23Q33925818-AACF6C87-1D4B-4FB2-9839-2DEEE41BA1E9Q34325999-0AE7350B-3C4A-4F7E-BC2C-FD21CEB5BE55Q37630593-3BC0C010-3505-4C06-9F87-7700068E6235Q38317226-00A62264-0538-40BD-BF47-63AEA2B1AD54Q38344759-B8AB3808-D55C-4EBC-831F-8D3150515A08Q38349558-171DBC18-95ED-4D0A-8383-D0F1DAF5FF97Q38378692-097414B7-321F-4FFE-A120-250A94177FC9Q39758686-0DE54F79-DD5C-48AA-8434-1BF2F58B25DCQ41981720-3C9477D6-B392-4477-8EBB-5EA1011C3ED4Q42632234-DCCEAC3B-4FE2-4F3C-BBA7-04A0540CAEF7Q45873294-EE80E116-A11C-4D25-A282-9538D595EC39
P2860
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Nucleic acid mutation analysis using catalytic DNA.
@en
type
label
Nucleic acid mutation analysis using catalytic DNA.
@en
prefLabel
Nucleic acid mutation analysis using catalytic DNA.
@en
P2093
P2860
P356
P1476
Nucleic acid mutation analysis using catalytic DNA.
@en
P2093
P2860
P356
10.1093/NAR/28.3.E9
P407
P577
2000-02-01T00:00:00Z