Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.
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Dysfunction of NMDA receptors in Alzheimer's diseaseA structural biology perspective on NMDA receptor pharmacology and functionNMDA receptor modulators: an updated patent review (2013-2014)Molecular bases of NMDA receptor subtype-dependent propertiesModulation of extrasynaptic NMDA receptors by synaptic and tonic zinc.Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission.AMPA receptor inhibition by synaptically released zincCell-type specific mechanisms of D-serine uptake and release in the brainThe NMDA Receptor and Schizophrenia: From Pathophysiology to Treatment.Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.Sensitivity of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to TCN 201 and TCN 213 in rat hippocampal slices.Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus.Recent insights into the mode of action of memantine and ketamineContext-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects.Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's diseaseMPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.Optical control of NMDA receptors with a diffusible photoswitch.Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia.Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation.Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors.Multiple roles of GluN2B-containing NMDA receptors in synaptic plasticity in juvenile hippocampus.Local and Use-Dependent Effects of β-Amyloid Oligomers on NMDA Receptor Function Revealed by Optical Quantal Analysis.Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.Pharmacology of triheteromeric N-Methyl-D-Aspartate Receptors.Context-Dependent Modulation of Excitatory Synaptic Strength by Synaptically Released Zinc.Synaptic Plasticity and Memory: New Insights from Hippocampal Left-Right Asymmetries.NMDA Receptor Internalization by Autoantibodies: A Reversible Mechanism Underlying Psychosis?The Regulation of GluN2A by Endogenous and Exogenous Regulators in the Central Nervous System.Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators.NMDA receptors: linking physiological output to biophysical operation.Glutamatergic neurotransmission in the prefrontal cortex mediates the suppressive effect of intra-prelimbic cortical infusion of BDNF on cocaine-seeking.GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity.Modulating synaptic NMDA receptors.Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties.Properties and molecular identity of NMDA receptors at synaptic and non-synaptic inputs in cerebellar molecular layer interneurons.Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
P2860
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P2860
Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Distinct functional and pharma ...... /GluN2A/GluN2B NMDA receptors.
@en
type
label
Distinct functional and pharma ...... /GluN2A/GluN2B NMDA receptors.
@en
prefLabel
Distinct functional and pharma ...... /GluN2A/GluN2B NMDA receptors.
@en
P2860
P1433
P1476
Distinct functional and pharma ...... 1/GluN2A/GluN2B NMDA receptors
@en
P2093
Hongjie Yuan
Stephen F Traynelis
P2860
P304
P356
10.1016/J.NEURON.2014.01.035
P407
P577
2014-03-01T00:00:00Z