Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.
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The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activationDJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive elementDifferential induction of mafF, mafG and mafK expression by electrophile-response-element activatorsSmall Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathwayAryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expressionRegulation of glutathione synthesisThe importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current stateThe antioxidant master glutathione and periodontal healthThe spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergeticsPolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesDysregulation of glutathione homeostasis in neurodegenerative diseasesThe Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseasesOxidative stress responses and NRF2 in human leukaemiaGlutathione synthesisRoles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degenerationRoles nrf2 plays in myeloid cells and related disordersEvidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosisNuclear Factor, Erythroid 2-Like 2 Regulates Expression of Type 3 Inositol 1,4,5-Trisphosphate Receptor and Calcium Signaling in Cholangiocytes.Tumor progression and the different faces of the PERK kinaseSmall maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:Quinone oxidoreductase1 geneNrf1 is critical for redox balance and survival of liver cells during developmentNrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasmc-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant inductionThe p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcriptionDelayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signalingNrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1High-throughput functional genomics identifies genes that ameliorate toxicity due to oxidative stress in neuronal HT-22 cells: GFPT2 protects cells against peroxideFlavonoids: modulators of brain function?An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophenNrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent mannerOridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive responseThe Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs4-Hydroxy-2-nonenal induces apoptosis by activating ERK1/2 signaling and depleting intracellular glutathione in intestinal epithelial cellsNrf2-dysregulation correlates with reduced synthesis and low glutathione levels in experimental autoimmune encephalomyelitisNrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
P2860
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P2860
Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Regulation of gamma-glutamylcy ...... the transcription factor Nrf2.
@en
type
label
Regulation of gamma-glutamylcy ...... the transcription factor Nrf2.
@en
prefLabel
Regulation of gamma-glutamylcy ...... the transcription factor Nrf2.
@en
P2093
P2860
P356
P1476
Regulation of gamma-glutamylcy ...... the transcription factor Nrf2.
@en
P2093
P2860
P304
33627-33636
P356
10.1074/JBC.274.47.33627
P407
P577
1999-11-01T00:00:00Z