about
Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoterGSTCD and INTS12 regulation and expression in the human lungGenome-wide association study identifies five loci associated with lung functionInterleukin-4 receptor alpha gene variants and allergic diseasePharmacogenetics, pharmacogenomics and airway diseaseSequence variants affecting eosinophil numbers associate with asthma and myocardial infarctionEffects of a range of beta2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cellsGenome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary functionGenome-wide association study to identify genetic determinants of severe asthma.Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.Integrative pathway genomics of lung function and airflow obstruction.Genome-wide association analysis identifies six new loci associated with forced vital capacityGenome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstructionGenome-wide association and large-scale follow up identifies 16 new loci influencing lung function.Haplotype estimation for biobank-scale data sets.Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort.PLAUR polymorphisms and lung function in UK smokers.Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences.Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.Second messengers, ion channels and pharmacology of airway smooth muscle.Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation.A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea.A sequence variant on 17q21 is associated with age at onset and severity of asthma.Pharmacogenetics of asthma.Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report.Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studiesCurrent progress in pharmacogenetics.Personalised prescribing for asthma--is pharmacogenetics the answer?The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model.A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation?Complications and mortality in hereditary hemorrhagic telangiectasia: A population-based study.The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterolThiazide diuretic prescription and electrolyte abnormalities in primary careEffect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro.
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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Ian P. Hall
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