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Genome-wide association study to identify genetic determinants of severe asthma.

Genome-wide association study to identify genetic determinants of severe asthma.

http://www.wikidata.org/entity/Q29417011

about

Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression Elucidating novel disease mechanisms in severe asthma Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma Respiratory reviews in asthma 2013 Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48.Assessment of asthma severity in adults with ever asthma: A continuous score.Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.The Wuhan-Zhuhai (WHZH) cohort study of environmental air particulate matter and the pathogenesis of cardiopulmonary diseases: study design, methods and baseline characteristics of the cohort.Genetic variation in HTR4 and lung function: GWAS follow-up in mouse.Systems biology of asthma and allergic diseases: a multiscale approach A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children.Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children Close correlation between season of birth and the prevalence of bronchial asthma in a Taiwanese population.The Association of GSDMB and ORMDL3 Gene Polymorphisms With Asthma: A Meta-Analysis Beta2 adrenergic receptor (ADRβ2) haplotype pair (2/4) is associated with severe asthma Genetics of allergic diseases.IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalk.Exome analysis of patients with concurrent pediatric inflammatory bowel disease and autoimmune disease.ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.A genome-wide association study of asthma symptoms in Latin American children.Genome-wide search identifies a gene-gene interaction between 20p13 and 2q14 in asthma.Severe asthma in children.Genes associated with RSV lower respiratory tract infection and asthma: the application of genetic epidemiological methods to understand causality.Airway reactivity and sphingolipids-implications for childhood asthma Asthma genetics and personalised medicine.Asthma Genetics in the Post-GWAS Era.IL1RL1 asthma risk variants regulate airway type 2 inflammation.17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells.Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma.Airway epithelial barrier function regulates the pathogenesis of allergic asthma.Genetic risk factors for the development of allergic disease identified by genome-wide association ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.β2 Agonists E3 ubiquitin ligase Cbl-b suppresses human ORMDL3 expression through STAT6 mediation.A pathway-based association study reveals variants from Wnt signalling genes contributing to asthma susceptibility.

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Genome-wide association study to identify genetic determinants of severe asthma.

http://www.wikidata.org/entity/Q29417011

description

2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Genome-wide association study to identify genetic determinants of severe asthma.

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Genome-wide association study to identify genetic determinants of severe asthma.

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type

label

Genome-wide association study to identify genetic determinants of severe asthma.

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Genome-wide association study to identify genetic determinants of severe asthma.

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prefLabel

Genome-wide association study to identify genetic determinants of severe asthma.

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Genome-wide association study to identify genetic determinants of severe asthma.

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THORAXJNL-2011-201262

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Genome-wide association study to identify genetic determinants of severe asthma

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A Bush

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A H Mansur

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A L James

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A Singapuri

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A W Musk

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Australian Asthma Genetics Consortium

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B A H Al-Momani

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D P Strachan

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K F Chung

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10.1136/THORAXJNL-2011-201262

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9

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67

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Matthew A. Brown

John W. Holloway

Neil C. Thomson

María Soler Artigas

Manuel A Ferreira

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2012-05-05T00:00:00Z

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genome-wide association study