Cbfa1 isoform overexpression upregulates osteocalcin gene expression in non-osteoblastic and pre-osteoblastic cells.
about
Down-regulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis.Cbfa1/Runx2-deficiency delays bone wound healing and locally delivered Cbfa1/Runx2 promotes bone repair in animal models.Runx2 overexpression in bone marrow stromal cells accelerates bone formation in critical-sized femoral defects.Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice.Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation.Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fracturesBone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes.Tissue engineering strategies for the future generation of dental implants.Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation.Runx2 and dental development.Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in miceBMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype.Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic developmentZfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo.Inducible expression of Runx2 results in multiorgan abnormalities in mice.Dose-dependent effects of Runx2 on bone development.
P2860
Q33636577-9CFFCDA4-2A32-422E-B135-F76F1F1C5073Q33721963-849E19A3-FAEC-4D13-9CCD-93CA4E9ABC6EQ34083291-E11FFDB2-FF93-459D-85F1-2B2B971640B4Q34333682-64EC0AFF-10A6-4338-949D-0E54CB0D1213Q35210378-B26B588A-B714-4DB8-B98A-660FA91807CBQ36293998-DC4F965A-3E1D-4357-9821-2F66451A7B43Q36324476-182FB9DA-4D70-49BA-9377-053C75945EC7Q36474294-BE8801C4-E7A3-49B2-A7A6-1EA29455E7EAQ36585580-5A7B192D-A7A7-4CB4-980C-FA8BCB3288F9Q36589550-6D09DD88-9296-47D8-8100-F72EEC6FF44BQ36616577-7C49E465-5B0A-4B4B-AE7D-2007706D78D8Q36655020-E6863026-262D-4219-B7BE-6AC26E9531DAQ36731376-92BA814D-3847-4A7A-98B8-99FFE0F43605Q37109508-F3309B38-B87F-462F-BE46-390B390D8A23Q37351658-950F7785-6EFC-4C2C-8520-6F188CEE2131Q37365273-BF7D6472-AB0F-4195-8C61-0D107E63969AQ37396635-F821E521-522E-4B99-B40F-6C5FDD13FB67
P2860
Cbfa1 isoform overexpression upregulates osteocalcin gene expression in non-osteoblastic and pre-osteoblastic cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Cbfa1 isoform overexpression u ...... ic and pre-osteoblastic cells.
@en
type
label
Cbfa1 isoform overexpression u ...... ic and pre-osteoblastic cells.
@en
prefLabel
Cbfa1 isoform overexpression u ...... ic and pre-osteoblastic cells.
@en
P2093
P1476
Cbfa1 isoform overexpression u ...... ic and pre-osteoblastic cells.
@en
P2093
P304
P356
10.1002/(SICI)1097-4644(19990915)74:4<596::AID-JCB9>3.3.CO;2-6
P577
1999-09-01T00:00:00Z