Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
about
Clarifying the mechanics of DNA strand exchange in meiotic recombinationCDK targets Sae2 to control DNA-end resection and homologous recombinationDNA resection in eukaryotes: deciding how to fix the breakTargeting DNA topoisomerase II in cancer chemotherapyDNA end resection: many nucleases make light workCollision of Trapped Topoisomerase 2 with Transcription and Replication: Generation and Repair of DNA Double-Strand Breaks with 5' AdductsDNA End Resection: Facts and MechanismsDNA double-strand break repair pathway choice and cancerRepair of strand breaks by homologous recombinationMammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesisStructural and functional analyses of the DMC1-M200V polymorphism found in the human populationNbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and RepairThe Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break RepairMre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairMechanism of repair of 5′-topoisomerase II–DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signalingCdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination.Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1Budding yeast Pch2, a widely conserved meiotic protein, is involved in the initiation of meiotic recombination.Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.Interactions between Mei4, Rec114, and other proteins required for meiotic DNA double-strand break formation in Saccharomyces cerevisiaeYeast axial-element protein, Red1, binds SUMO chains to promote meiotic interhomologue recombination and chromosome synapsis.Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme.Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases.RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination.Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation.Processing of damaged DNA ends for double-strand break repair in mammalian cellsInitiation of meiotic homologous recombination: flexibility, impact of histone modifications, and chromatin remodelingConnecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombinationRelative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell linesA covalent protein-DNA 5'-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1)Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctionsCollaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repairNumerical analysis of etoposide induced DNA breaksIntegrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screenMeiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanismsMouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPaseMeiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in miceThe TopoVIB-Like protein family is required for meiotic DNA double-strand break formationMeiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1.
P2860
Q22122460-197CD212-F2E6-427B-B2B5-1D257C789865Q24328867-BC0B9C94-7511-4E59-BBB6-552430C3CB4CQ24603592-D4185DD3-CF17-484C-8301-6875A2D18C52Q24649711-F3414872-04BD-44CA-8AD6-A7A9F2E7E74CQ24654725-1E4CD869-7582-4295-8F5B-041812E3DE08Q26744712-3C7BAC91-00D4-4E9E-A6D6-89AB90DB4863Q26744798-A77527BF-EAF8-4D3B-8B6C-789C22D4E8E9Q26996175-F5B44B16-B501-4BDB-BDB7-E75CEEB68501Q27012688-A3922E3A-59BE-4FF4-9F3C-5E1C87F26E82Q27340183-2E5F4D27-CDAD-46AD-AA27-32083FC6C87BQ27650895-D34885BC-20BF-4187-9E94-93D1D5A1934AQ27657670-D914F459-95B5-48A3-A19E-93667D1C4946Q27667404-6EA78E0A-5933-46AD-A101-E3FBA7C83BEEQ27674627-563DFB06-5FC6-4D1C-B5D6-6482B19C0F16Q27674755-22CFD938-0A47-4EA4-BE59-96B1200DEEB0Q27681202-5B813D37-5679-468A-8DFE-23DF25DA10A9Q27929793-7548D00C-0D35-4557-82A1-4DFCD3F009FDQ27930407-B0276152-A4FF-4BD5-BEF8-1EAFD5B1E7DCQ27930826-EF8436BC-52D6-4D55-8B5F-1BBFB88BE654Q27930908-5F5531DE-649B-4005-B626-11A9711E5B4AQ27935897-1B70278D-C105-4323-947D-AC7688676C4DQ27936223-99BDABDD-6012-403B-9142-8E3CEB56DEBDQ27936967-B1BACD2B-6CB9-49E6-860C-1D8827373531Q27939123-37347EAB-4395-4D03-98E3-75DA8F79DECBQ27939265-8B2ACEF5-DD6D-4C90-BF70-533303329C6BQ27940335-EEF24718-698A-4944-A516-715829208983Q28000148-7D231EFB-05DE-49B9-9618-52FEBA4FC222Q28261460-60654640-DF78-499E-BF96-764662B6BA19Q28261702-804FEEEE-15AC-439E-A378-645B887EFACAQ28269335-71086000-D49E-42A0-9D00-97744406C44BQ28288765-B8F175E7-591A-4C06-A958-6E3E34B53E71Q28301386-596F5C82-A4A7-4CD2-8AAA-FE6B9EFFC69EQ28472620-850C7B20-3AE5-47B9-BC64-1E0C95F05979Q28475598-B1A46027-A78B-493C-B6A3-4FD6189C77D8Q28484181-E9B2CFF2-D67A-42F4-B6A1-5E1BC256E771Q28585141-06737FB7-B6DE-4F8C-B584-4A5035FFC02AQ28586590-ACF72EBE-47ED-4713-B16B-991693BE31E6Q28592420-3357EB69-7DCD-4D5E-AC88-7FD99740A2D3Q28592802-81CDA523-283C-40FA-AE31-621D66FD9BCFQ28594654-7BFDF53D-7F4C-48C1-9F63-B41342340F2E
P2860
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
@en
type
label
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
@en
prefLabel
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
@en
P2093
P2860
P356
P1433
P1476
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
@en
P2093
Matthew J Neale
Scott Keeney
P2860
P2888
P304
P356
10.1038/NATURE03872
P407
P577
2005-08-01T00:00:00Z
P5875
P6179
1031191047