Antisense oligonucleotides against receptor kinase GRK2 disrupt target selectivity of beta-adrenergic receptors in atrial myocytes.
about
Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes.Downregulation of Spinal G Protein-Coupled Kinase 2 Abolished the Antiallodynic Effect of ElectroacupunctureTransient decrease in nociceptor GRK2 expression produces long-term enhancement in inflammatory painHeterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinaseG protein-independent inhibition of GIRK current by adenosine in rat atrial myocytes overexpressing A1 receptors after adenovirus-mediated gene transfer.Overexpression of monomeric and multimeric GIRK4 subunits in rat atrial myocytes removes fast desensitization and reduces inward rectification of muscarinic K(+) current (I(K(ACh))). Evidence for functional homomeric GIRK4 channels.GRK3 mediates desensitization of CRF1 receptors: a potential mechanism regulating stress adaptation.Overexpression of beta 1 and beta 2 adrenergic receptors in rat atrial myocytes. Differential coupling to G protein-gated inward rectifier K(+) channels via G(s) and G(i)/o.Transfection of a phosphatidyl-4-phosphate 5-kinase gene into rat atrial myocytes removes inhibition of GIRK current by endothelin and alpha-adrenergic agonists.Role of a novel nociceptor autocrine mechanism in chronic pain.
P2860
Q31650674-08D7CAB5-66F9-4D31-A01A-65384DFFA123Q35598841-EA678F6E-DE94-47C3-ADC4-2AA9426F04A2Q36207533-A864AF60-DA59-4CA4-BFC0-F2BC008A3415Q36412235-049407E5-3B7A-40D1-AB75-0CA07E363C54Q38353449-B308E484-78E8-4850-88C3-6D484A84C8B7Q40802134-EF78D19C-7E6A-4638-8FC1-B1EACBF4FE29Q40821076-D7C90781-CB46-4568-9B35-AB959863800CQ43701650-9C3477E4-6D52-4FAC-A14E-7713E9982CE4Q44174080-09370AD9-9BED-4299-BD92-16AF8610E438Q46337882-9DF253B2-DB5C-4ED8-BC03-3127A158D12B
P2860
Antisense oligonucleotides against receptor kinase GRK2 disrupt target selectivity of beta-adrenergic receptors in atrial myocytes.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Antisense oligonucleotides aga ...... receptors in atrial myocytes.
@en
type
label
Antisense oligonucleotides aga ...... receptors in atrial myocytes.
@en
prefLabel
Antisense oligonucleotides aga ...... receptors in atrial myocytes.
@en
P2093
P2860
P1433
P1476
Antisense oligonucleotides aga ...... receptors in atrial myocytes.
@en
P2093
P2860
P304
P356
10.1016/S0014-5793(99)00594-3
P407
P577
1999-05-01T00:00:00Z