A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells.
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Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factorProliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cellsPOU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response elementDifferential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cellsThe human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domainThe DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activityDifferential regulation of different human papilloma virus variants by the POU family transcription factor Brn-3aBrn-3a neuronal transcription factor functional expression in human prostate cancerThe different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding siteThe ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elementsCardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expressionThe Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteinsThe BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosisMouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3aThe opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domainShort isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif bindingp53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factorThe Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoterBrn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expressionRegulation of DNA virus transcription by cellular POU family transcription factors.The HPV Cellular Transactivator Brn-3a Can Be Used to Predict Cervical Adenocarcinoma and Squamous Carcinoma Precancer Lesions in the Developed and Developing Worlds.The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells.The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo.Whole number, distribution and co-expression of brn3 transcription factors in retinal ganglion cells of adult albino and pigmented rats.The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression.Transcription factors interacting with herpes simplex virus alpha gene promoters in sensory neuronsHerpes simplex virus type 1 and bovine herpesvirus 1 latency.Targeting Brn-3b in breast cancer therapy.Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dicationA novel Brn3-like POU transcription factor expressed in subsets of rat sensory and spinal cord neurons.Pou4f2 knock-in Cre mouse: A multifaceted genetic tool for vision researchers.Biomarkers in cervical precancer management: the new frontiers.The HPV-activating cellular transcription factor Brn-3a is overexpressed in CIN3 cervical lesions.Activation of the herpes simplex virus immediate-early gene promoters by neuronally expressed POU family transcription factors.Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein.The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells.Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor.Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter.The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.PDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter.
P2860
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P2860
A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
A novel POU family transcripti ...... ion pattern in neuronal cells.
@en
type
label
A novel POU family transcripti ...... ion pattern in neuronal cells.
@en
prefLabel
A novel POU family transcripti ...... ion pattern in neuronal cells.
@en
P2093
P2860
P356
P1476
A novel POU family transcripti ...... ion pattern in neuronal cells.
@en
P2093
Budrahan VS
Latchman DS
Lillycrop KA
Terrenghi G
P2860
P304
P356
10.1093/NAR/20.19.5093
P407
P577
1992-10-01T00:00:00Z