The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells. - Wikidata - wikimedia - TriplyDB

The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.

The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.

http://www.wikidata.org/entity/Q40411122

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Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo.The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression.Targeting Brn-3b in breast cancer therapy.The HPV-activating cellular transcription factor Brn-3a is overexpressed in CIN3 cervical lesions.Activation of the herpes simplex virus immediate-early gene promoters by neuronally expressed POU family transcription factors.Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein.Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor.Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor.Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor.The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c.Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors.Distinct protein kinases regulate SNAP-25 expression in chromaffin cells.The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21(CIP1/Waf1).

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P2860

The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.

http://www.wikidata.org/entity/Q40411122

description

1994 nî lūn-bûn

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1994年の論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

@zh-mo

1994年論文

@zh-tw

1994年论文

@wuu

1994年论文

@zh

1994年论文

@zh-cn

name

The DNA target site for the Br ...... al of serum in neuronal cells.

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type

label

The DNA target site for the Br ...... al of serum in neuronal cells.

@en

prefLabel

The DNA target site for the Br ...... al of serum in neuronal cells.

@en

P1433

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Nucleic Acids Research

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The DNA target site for the Br ...... val of serum in neuronal cells

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D S Latchman

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K A Lillycrop

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P J Morris

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T Moroy

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V Budhram-Mahadeo

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P2860

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs

A novel POU homeodomain gene specifically expressed in cells of the developing mammalian nervous system

The human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domain

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency

Expression of a large family of POU-domain regulatory genes in mammalian brain development

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a

Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid

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3092-3098

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scholarly article

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10.1093/NAR/22.15.3092

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15

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22

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1994-08-01T00:00:00Z

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15133169

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8065921

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310280

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