Probing of the spliceosome with site-specifically derivatized 5' splice site RNA oligonucleotides

Probing of the spliceosome with site-specifically derivatized 5' splice site RNA oligonucleotides

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http://www.wikidata.org/entity/Q38333283
The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice siteThe 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase siteDefining a 5' splice site by functional selection in the presence and absence of U1 snRNA 5' end.Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation.Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center.Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site.Analysis of site-specific protein-RNA cross-links in isolated RNP complexes, combining affinity selection and mass spectrometry.spp42, identified as a classical suppressor of prp4-73, which encodes a kinase involved in pre-mRNA splicing in fission yeast, is a homologue of the splicing factor Prp8p.
P2860

Probing of the spliceosome with site-specifically derivatized 5' splice site RNA oligonucleotides

Item
http://www.wikidata.org/entity/Q38333283
description
1998 nî lūn-bûn
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1998年の論文
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1998年学术文章
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1998年学术文章
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1998年学术文章
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1998年学术文章
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1998年學術文章
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1998年學術文章
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1998年學術文章
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name
Probing of the spliceosome wit ...... lice site RNA oligonucleotides
@en
type
label
Probing of the spliceosome wit ...... lice site RNA oligonucleotides
@en
prefLabel
Probing of the spliceosome wit ...... lice site RNA oligonucleotides
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Probing of the spliceosome wit ...... lice site RNA oligonucleotides
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932