The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6
about
Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activatorsA nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP familyGlucocorticoid-and non-glucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leucocytes in vivoHemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contendersInduction of endogenous retroviral gene product (SU) as an acute-phase protein by IL-6 in murine hepatocytesProteomics mapping of cord blood identifies haptoglobin "switch-on" pattern as biomarker of early-onset neonatal sepsis in preterm newbornsSynovial fluid proteins differentiate between the subtypes of juvenile idiopathic arthritis.Identification of haptoglobin as an angiogenic factor in sera from patients with systemic vasculitis.Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1.Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes.Hypoxia-inducible factor-1alpha enhances haptoglobin gene expression by improving binding of STAT3 to the promoter.Liver receptor homolog 1 is a negative regulator of the hepatic acute-phase response.Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat.Chimerism in humans after intragenic recombination at the haptoglobin locus during early embryogenesisProteomics/diagnosis of chorioamnionitis and of relationships with the fetal exposome.An essential amino acid induces epithelial beta -defensin expressionNuclear factors interacting with an interleukin-6 responsive element of rat alpha 2-macroglobulin gene.Individual variation in levels of haptoglobin-related protein in children from GabonBlood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study.Induction of the mouse serum amyloid A3 gene by cytokines requires both C/EBP family proteins and a novel constitutive nuclear factor.The cytokine response element of the rat alpha 1-acid glycoprotein gene is a complex of several interacting regulatory sequencesDistinct regulation of the interleukin-1 and interleukin-6 response elements of the rat haptoglobin gene in rat and human hepatoma cells.Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene.A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.Molecular analysis of the differential hepatic expression of rat kininogen family genesInsulin is a prominent modulator of the cytokine-stimulated expression of acute-phase plasma protein genes.Induction by interleukin-6 of interferon regulatory factor 1 (IRF-1) gene expression through the palindromic interferon response element pIRE and cell type-dependent control of IRF-1 binding to DNA.Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements.Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.Interleukin-1-mediated enhancement of mouse factor B gene expression via NF kappa B-like hepatoma nuclear factor.Constitutive and IL-6-induced nuclear factors that interact with the human C-reactive protein promoter.Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseasesThe two C/EBP isoforms, IL-6DBP/NF-IL6 and C/EBP delta/NF-IL6 beta, are induced by IL-6 to promote acute phase gene transcription via different mechanisms.A base substitution in the promoter associated with the human haptoglobin 2-1 modified phenotype decreases transcriptional activity and responsiveness to interleukin-6 in human hepatoma cells.The analysis of the human hemopexin promoter defines a new class of liver-specific genesDNA polymorphisms in the controlling region of the human haptoglobin genes: a molecular explanation for the haptoglobin 2-1 modified phenotype.Post-transcriptional control of negative acute phase genes by transforming growth factor beta.Dual control of C-reactive protein gene expression by interleukin-1 and interleukin-6.
P2860
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P2860
The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The human haptoglobin gene pro ...... otein induced by interleukin-6
@en
type
label
The human haptoglobin gene pro ...... otein induced by interleukin-6
@en
prefLabel
The human haptoglobin gene pro ...... otein induced by interleukin-6
@en
P2860
P1433
P1476
The human haptoglobin gene pro ...... otein induced by interleukin-6
@en
P2093
P2860
P304
P407
P577
1989-04-01T00:00:00Z