Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding.
about
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristicsLAG-3, a novel lymphocyte activation gene closely related to CD4Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex moleculesPathogenesis of human immunodeficiency virus infectionRole of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infectionEffects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoproteinEvolution of a species-specific determinant within human CRM1 that regulates the post-transcriptional phases of HIV-1 replicationMolecular approaches to the study of B cell epitopes.Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropismThe Ixodes scapularis salivary protein, salp15, prevents the association of HIV-1 gp120 and CD4Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 moleculeBinding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesisMutational analysis of the virus and monoclonal antibody binding sites in MHVR, the cellular receptor of the murine coronavirus mouse hepatitis virus strain A59Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis.Antibodies to CD4 in individuals infected with human immunodeficiency virus type 1.CD4-independent human immunodeficiency virus infection involves participation of endocytosis and cathepsin B.Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events.Reduced monomeric CD4 is the preferred receptor for HIVFunctional domains of the poliovirus receptor.Crystal structure of an HIV-binding recombinant fragment of human CD4.Postentry restriction of Mason-Pfizer monkey virus in mouse cellsTheoretical and practical aspects of antigenized antibodies.Determinants of human immunodeficiency virus type 1 entry in the CDR2 loop of the CD4 glycoprotein.Artificial mutations and natural variations in the CD46 molecules from human and monkey cells define regions important for measles virus binding.The auto-regulation model: a unified concept of how HIV regulates its infectivity, pathogenesis and persistence.Mouse hepatitis virus strain A59 and blocking antireceptor monoclonal antibody bind to the N-terminal domain of cellular receptor.Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 bindingThe human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure.Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding.Antibody raised against soluble CD4-rgp120 complex recognizes the CD4 moiety and blocks membrane fusion without inhibiting CD4-gp120 binding.Human CRM1 augments production of infectious human and feline immunodeficiency viruses from murine cells.Homolog-scanning mutagenesis reveals poliovirus receptor residues important for virus binding and replication.The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.Blocking of human immunodeficiency virus infection depends on cell density and viral stock ageActive immunity against the CD4 receptor by using an antibody antigenized with residues 41-55 of the first extracellular domain.Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor bindingSeveral CD4 domains can play a role in human immunodeficiency virus infection in cells.Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity.CD4/immunoglobulin interaction: implications for immune physiology and autoimmunity.
P2860
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P2860
Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Substitution of murine for hum ...... ritical for HIV-gp120 binding.
@en
type
label
Substitution of murine for hum ...... ritical for HIV-gp120 binding.
@en
prefLabel
Substitution of murine for hum ...... ritical for HIV-gp120 binding.
@en
P2093
P356
P1433
P1476
Substitution of murine for hum ...... ritical for HIV-gp120 binding.
@en
P2093
Clayton LK
Ramachandran H
Reinherz EL
Steinbrich R
P2888
P304
P356
10.1038/335363A0
P407
P577
1988-09-01T00:00:00Z
P6179
1007957203