Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides.
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Enhanced exon-skipping induced by U7 snRNA carrying a splicing silencer sequence: Promising tool for DMD therapyChimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo.Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals.Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicingSynthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicingAntisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB.Ligand-induced sequestering of branchpoint sequence allows conditional control of splicing.Alternative splicing of exon 10 in the tau gene as a target for treatment of tauopathies.Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements.Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies.A negatively acting bifunctional RNA increases survival motor neuron both in vitro and in vivo.The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.An artificial riboswitch for controlling pre-mRNA splicing.Detection of splicing aberrations caused by BRCA1 and BRCA2 sequence variants encoding missense substitutions: implications for prediction of pathogenicityReprogramming cellular behavior with RNA controllers responsive to endogenous proteinsDefining the factors that contribute to on-target specificity of antisense oligonucleotides.Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides.A G-rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing.Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.A G-tract element in apoptotic agents-induced alternative splicing.Targeting RNA splicing for disease therapy.Modulating the expression of disease genes with RNA-based therapy.Delivery of bifunctional RNAs that target an intronic repressor and increase SMN levels in an animal model of spinal muscular atrophy.Alternative splicing and disease.Splicing therapeutics in SMN2 and APOB.Targeting RNA-splicing for SMA treatment.Redirecting splicing with bifunctional oligonucleotides.My road to alternative splicing control: from simple paths to loops and interconnections.New CD20 alternative splice variants: molecular identification and differential expression within hematological B cell malignancies.Targeting Splicing in the Treatment of Human DiseaseAntisense therapeutics: New ways to nudge splicing.Alternative Splicing as a Target for Cancer Treatment.
P2860
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P2860
Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Reprogramming alternative pre- ...... ng antisense oligonucleotides.
@en
type
label
Reprogramming alternative pre- ...... ng antisense oligonucleotides.
@en
prefLabel
Reprogramming alternative pre- ...... ng antisense oligonucleotides.
@en
P2093
P2860
P356
P1476
Reprogramming alternative pre- ...... ng antisense oligonucleotides.
@en
P2093
Benoit Chabot
Isabelle Dion
Jonathan Villemaire
Sherif Abou Elela
P2860
P304
50031-50039
P356
10.1074/JBC.M308897200
P407
P577
2003-09-30T00:00:00Z