The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.
about
Mutational analysis of the v-Rel dimerization interface reveals a critical role for v-Rel homodimers in transformationAstrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegenerationNew insights into the role of nuclear factor-kB in cell growth regulationNuclear factor kappa B: a marker of chemotherapy for human stage IV gastric carcinomaRelB-dependent stromal cells promote T-cell leukemogenesisLoss of IkappaB alpha-mediated control over nuclear import and DNA binding enables oncogenic activation of c-RelMapping of a serine-rich domain essential for the transcriptional, antiapoptotic, and transforming activities of the v-Rel oncoprotein.Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.NF-κB and cancer: a paradigm of Yin-Yang.IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphomach-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein.CAPERalpha is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein v-Rel.Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.Expression of constitutively active IkappaB beta in T cells of transgenic mice: persistent NF-kappaB activity is required for T-cell immune responsesMultiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein.IkappaBalpha overexpression delays tumor formation in v-rel transgenic mice.Downregulation of RelA (p65) by Rapamycin Inhibits Murine Adipocyte Differentiation and Reduces Fat Mass of C57BL/6J Mice despite High Fat Diet.p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice.Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50.MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB.The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice.Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis
P2860
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P2860
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.
description
1996 nî lūn-bûn
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1996年の論文
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1996年学术文章
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1996年学术文章
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1996年学术文章
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1996年学术文章
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1996年学术文章
@zh-sg
1996年學術文章
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1996年學術文章
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1996年學術文章
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name
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.
@en
type
label
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.
@en
prefLabel
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.
@en
P2093
P2860
P1433
P1476
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice.
@en
P2093
P2860
P304
P407
P577
1996-07-01T00:00:00Z