Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
about
Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagyDJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathwayKeap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.The in vivo gene expression signature of oxidative stressAdvances in mechanisms of anti-oxidationSulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell ResistanceVariations in Antioxidant Genes and Male InfertilityRoles nrf2 plays in myeloid cells and related disordersRelationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegansRedox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degronGenetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.Crystal structure of quinone reductase 2 in complex with resveratrolNrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genesNF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protectionNrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosisWhen NRF2 talks, who's listening?Reactive oxygen production induced by the gut microbiota: pharmacotherapeutic implicationsSmall molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agentsDietary chemoprevention strategies for induction of phase II xenobiotic-metabolizing enzymes in lung carcinogenesis: A reviewReactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosisIncreased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)Basic principles and emerging concepts in the redox control of transcription factorsSrc subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expressionOncogene PKCε controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2An aryl hydrocarbon receptor induces VEGF expression through ATF4 under glucose deprivation in HepG2Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big DataNrf2 signaling and cell survivalMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseInhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosisThe clinical potential of influencing Nrf2 signaling in degenerative and immunological disordersNRF2-regulation in brain health and disease: implication of cerebral inflammationEmerging role of Nrf2 in adipocytes and adipose biologyThe sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencingModulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseasesNrf2:INrf2 (Keap1) signaling in oxidative stress
P2860
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P2860
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Modulation of gene expression ...... ne clusters for cell survival.
@en
type
label
Modulation of gene expression ...... ne clusters for cell survival.
@en
prefLabel
Modulation of gene expression ...... ne clusters for cell survival.
@en
P2093
P356
P1476
Modulation of gene expression ...... ne clusters for cell survival.
@en
P2093
Hozumi Motohashi
Masayuki Yamamoto
Mi-Kyoung Kwak
Nobunao Wakabayashi
Thomas W Kensler
P304
P356
10.1074/JBC.M211898200
P407
P577
2002-12-27T00:00:00Z