The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein.
about
Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell deathBtf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19KCaspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signalingThe interferon stimulated gene 54 promotes apoptosisharakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19KMovement of Bax from the cytosol to mitochondria during apoptosisRegulation of apoptosis by viral gene productsLamin proteolysis facilitates nuclear events during apoptosisAdenoviral vectors for prodrug activation-based gene therapy for cancerBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreThe cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude miceSynergistic role of E1A-binding proteins and tissue-specific transcription factors in differentiationInduction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactionsViral control of mitochondrial apoptosisMtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XLBax and Bak independently promote cytochrome C release from mitochondriaBax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesisAlpha cyano-4-hydroxy-3-methoxycinnamic acid inhibits proliferation and induces apoptosis in human breast cancer cellsBax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XLRegulation of the cell cycle and apoptosis by the oncogenes of adenovirusDownregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents.Resistance to induced apoptosis in the human neuroblastoma cell line SK-N-SH in relation to neuronal differentiation. Role of Bcl-2 protein family.Role of the Bcl-2 gene family in prostate cancer progression and its implications for therapeutic intervention.Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A.Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis.Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage.Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles.The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cellsDNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cellsThe domains of apoptosis: a genomics perspective.Adenovirus E3-6.7K maintains calcium homeostasis and prevents apoptosis and arachidonic acid release.Adenovirus infection of primary malignant lymphoid cells.Persistent gamma-herpesvirus infections: what can we learn from an experimental mouse model?hTERT extends the life of human fibroblasts without compromising type I interferon signaling.The essential role of evasion from cell death in cancer.Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function.Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria.
P2860
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P2860
The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The E1B 19K protein blocks apo ...... d death-promoting Bax protein.
@en
type
label
The E1B 19K protein blocks apo ...... d death-promoting Bax protein.
@en
prefLabel
The E1B 19K protein blocks apo ...... d death-promoting Bax protein.
@en
P2093
P356
P1433
P1476
The E1B 19K protein blocks apo ...... d death-promoting Bax protein.
@en
P2093
P304
P356
10.1101/GAD.10.4.461
P577
1996-02-01T00:00:00Z